Krystyna Barbara Zakrzewska
Researcher
Department of Experimental and Clinical Medicine
University of Firenze
Italy
Biography
Born in Warsaw (Poland) on 19.02.1958 Degree in Biology with Microbiology Specialization at the University of Warsaw (1982). Researcher at the Department of Biology and Immunology at the Faculty of Medicine in Warsaw (1982). Degree in Biological Sciences at the University of Florence (1985). Anna Villa Rusconi Foundation scholarship for a study stay at the Department of Medical Microbiology at University College in London (1990). A scholarship awarded by the Istituto Superiore di Sanità in Rome for research aimed at combating AIDS (1991). A three-year scholarship awarded by the Orto Bartolomei Virological Research Foundation Courses to carry out research on human parvovirus B19 at a virology laboratory at the Department of Public Health of the University of Florence (1992). Scientific activity: Participation in national and international research projects concerning epidemiology, pathogenesis and laboratory diagnosis of viral diseases.
Research Interest
Study of two viral subtypes, "O" (original) and "D" (derived) of H1N1 influenza viruses • Molecular bases of pathogenicity of influenza viruses in a murine model • Artifact of biology techniques molecular model for parvovirus B19 genomic research • Epidemiological survey on the diffusion of parvovirus B19 infection in Italy • Role of parvovirus B19 infection in immunodeficient antiblastic chemotherapy subjects during leukemia and in patients undergoing bone marrow transplantation kidney transplantation. • Surveillance of B19 virus infection during AIDS as a cause of chronic anemia • Study of genetic variability of human parvovirus B19 • Transmission of parvovirus B19 infection with emoderivati: control of coagulation factor concentrates • Role of human parvovirus B19 in hemophilic arthropathy • Molecular bases of human parvovirus persistence B19 • Role of human parvovirus B19 in pathogenesis of systemic sclerosis • Distribution of the three genotypes of parvovirus B19 in tissues of individuals without clinical manifestations attributable to B19 infection • Study of the association between BK virus re-activation and hemorrhagic cysteine ​​in subjects undergoing bone marrow transplantation • BKV and JCV infections in AIDS patients • Diffusion of parv4 infection, affected tissues, persistence
Publications
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Bonizzoli, Manuela; Arvia, Rosaria; di Valvasone, Simona; Liotta, Francesco; Zakrzewska, Krystyna; Azzi, Alberta; Peris, Adriano (2016). Human herpesviruses respiratory infections in patients with acute respiratory distress (ARDS). MEDICAL MICROBIOLOGY AND IMMUNOLOGY, vol. 205, pp. 371-379, ISSN:0300-8584
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Urso, Carmelo; Pierucci, Federica; Sollai, Mauro; Arvia, Rosaria; Massi, Daniela; Zakrzewska, Krystyna (2016). Detection of Merkel cell polyomavirus and human papillomavirus DNA in porocarcinoma. JOURNAL OF CLINICAL VIROLOGY, vol. 78, pp. 71-73, ISSN:1386-6532
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Arvia, Rosaria; Sollai, Mauro; Pierucci, Federica; Urso, Carmelo; Massi, Daniela; Zakrzewska, Krystyna (2017). Droplet digital PCR (ddPCR) vs quantitative real-time PCR (qPCR) approach for detection and quantification of Merkel cell polyomavirus (MCPyV) DNA in formalin fixed paraffin embedded (FFPE) cutaneous biopsies. JOURNAL OF VIROLOGICAL METHODS, vol. 246, pp. 15-20, ISSN:0166-0934