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Mirella Coppo

Researcher
Department of Experimental and Clinical Medicine
University of Firenze
Italy

Biography

Qualifications • 1982 Degree in Biological Sciences at the University of Florence • 1985 qualified as a Biologist Profession passing the state exam at the University of Florence • March 9 to July 6 1989 Course updated on the study "Modeling experimental applied to the study of drugs" at the Department of Preclinical and Clinical Pharmacology "M Aiazzi Mancini", University of Florence. Career • January 1991 Assistant Engineer at the General Medical and Medical Therapy Clinic. • November 1997 a technical assistant graduated from the Institute of Clinical General Medicine and Cardiology • January 2005 researcher confirmed at Department of Critical Area Department of General Medical Clinic and Specialist Clinics (MED46). Business activity Inserted in the agreement signed with the Careggi Hospital Hospital under the law 761/79 with effect from 01/4/1991 with the following equations: • 01/4/1991 Level VI, professional operator profile • 01/11 / 1997 senior level healthcare professional (ex-biologist IX healthcare level) • 01/01/2005 researcher with confirmation between staff at departmental organizational structures of AOUC (SOD cardiology General I) Responsible for the dose of plasma catecholamines, gene polymorphism research for MTHFR; collaborates with the staff of SOD Aterotrombotic Diseases in Searching the Polymorphisms of V Leiden Factor and the Prothrombin Gene, monitoring of heparin therapy, therapy with antipyretic drugs, and research of antibodies for heparin-induced platelet function.

Research Interest

He participated in platelet physiopathology studies with particular regard to the methodological aspects by applying radioimmunoassay techniques for the determination of arachidonic acid derivatives, of chromogenic methods for the determination of coagulative and fibrinolytic plasma activities. It also employed immunologic enzyme techniques for the determination of degradation products of fibrinolysis and coagulation inhibitors.His researches were mainly oriented towards the study of local autocrine systems with particular interest in the role of the sympathetic cardiac system in the modulation of coronary tone in unstable angina (Neri Serneri et al. Circulation 1993) and in the early stages of the development of hypertrophy physiological athlete (NS et al. Circ Res 2001). More recently, the involvement of the sympathetic vascular arm system in the pathogenesis of Raynaud's phenomenon (Microvasc Res 2006) has been demonstrated.

Publications

  • L. Fallai; V. Maestripieri; A. Berni; M. Coppo; M. Bandinelli; C. Tozzetti; L. Naldi; R. Abbate; L. Poggesi; M. Boddi. (2012). The activation of lymphocyte renin-angiotensin system is modulated in the presence of low-grade inflammation in the hypertensive and obese patient. MINERVA CARDIOANGIOLOGICA, vol. 60, pp. 113-116, ISSN: 0026-4725

  • L. Fallai; A. Berni; C. Tozzetti; L. Naldi; M. Bandinelli; M. Coppo; R. Abbate; L. Poggesi; M. Boddi. (2012). Low-grade inflammation modulates T-lymphocyte renin-angiotensin system activation in hypertensives and obeses. INTERNAL AND EMERGENCY MEDICINE, pp. 509-509, ISSN: 1970-9366

  • L. Fallai; A. Berni; V. Maestripieri; M. Bandinelli; M. Coppo; R. Abbate; L. Poggesi; M. Boddi. (2012). Low-grade inflammation modulates T-lymphocyte Renin-Angiotensin System activation in hypertensives and obeses. ENGLISH DIAGNOSIS, vol. 4, pp. 56-56, ISSN: 2240-4821

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