Claudia Vergelli
Researcher
Department of Neuroscience, Area of ​​Pharmacy and Child
University of Florence
Italy
Biography
Claudia Vergelli graduated in Pharmaceutical Chemistry and Technology at the Pharmacy Faculty of the University of Florence in July 1997, with a vote 110 and Lode / 110, with an experimental thesis titled: "Synthesis, antiinocyte activity-structure correlations and study of mechanism of action of 4-amino-5-vinyl-3 (2H) -pyridazinones and related compounds. " In May 1998 she obtained her degree in Pharmacist Profession. From May 1998 to April 2000 he has been involved in scientific collaboration at the Department of Pharmaceutical Sciences of the University of Florence. In April 2003 he acquired the title of Doctor of Chemistry and Technology Research at the Department of Pharmaceutical Sciences with a thesis titled "Molecular Modifications of Nitraquazone analogs, potent and selective inhibitors of isoenzymes 4 and 5 of phosphodiesterases." From May 2003 to March 2006: has been the holder of a research grant at the Department of Pharmaceutical Sciences titled "Optimization of the Molecular Flexibility Nitraquazone analogs structure, active as PDE4 inhibitors and potentially useful in asthma therapy of atopic dermatitis ". From April 2006 to March 2007 she has held a position as a Researcher at the Department of Pharmaceutical Sciences at the University of Florence: Research Program: "Optimizing the structure of active pyridazinone derivatives as PDE4 inhibitors, potentially useful in asthma and chronic obstructive bronchitis" for the CHIM08 scientific-disciplinary field. In 2007 he was the winner of the competition as Researcher in the scientific-disciplinary field CHIM08 at the Department of Pharmaceutical Sciences at the University of Florence, where he currently conducts his research activity. Since March 2008 she has been supporting the course of the Medicinal Analysis III (C.L: Pharmacy). Since March 2013 he has been supporting and has been in charge of a module (1CFU) on the recognition of metallic substances during the analysis of Medicinal Products III (CL Pharmacy). In 2013-2014 he will hold support activities and will hold a module in the courses of Analysis of Medicines III (A-L) and (M-Z).
Research Interest
Pharmaceutical chemistry
Publications
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Crocetti, Letizia; Schepetkin, Igor A.; Ciciani, Giovanna; Giovannoni, Maria Paola; Guerrini, Gabriella; Iacovone, Antonella; Khlebnikov, Andrei I.; Kirpotina, Liliya N.; Quinn, Mark T.; Vergelli, Claudia (2016). Synthesis and pharmacological evaluation of indole derivatives as deaza analogues of potent human neutrophil elastase inhibitors. DRUG DEVELOPMENT RESEARCH, vol. 77, pp. 285-299, ISSN:1098-2299
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Guerrini, Gabriella; Ciciani, Giovanna; Crocetti, Letizia; Daniele, Simona; Ghelardini, Carla; Giovannoni, Maria Paola; Lorenzo Di Cesare Mannelli, ; Martini, Claudia; Vergelli, Claudia (2017). Synthesis and pharmacological evaluation of novel GABAA subtype receptor ligands with potential anxiolytic-like and anti-hyperlagesic effect. JOURNAL OF HETEROCYCLIC CHEMISTRY, pp. 0-0, ISSN:1943-5193
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Vergelli, Claudia; Schepetkin, Igor A.; Ciciani, Giovanna; Cilibrizzi, Agostino; Crocetti, Letizia; Giovannoni, Maria Paola; Guerrini, Gabriella; Iacovone, Antonella; Kirpotina, Liliya N.; Ye, Richard D.; Quinn, Mark T. (2017). Synthesis of five and six-membered N-phenylacetamido substituted heterocycles as formyl peptide receptor agonists. DRUG DEVELOPMENT RESEARCH, vol. 78, pp. 49-62, ISSN:1098-2299
