Elisabetta Meacci
Associate Professor
Department of Biomedical, Experimental and Clinical Sciences
University of Florence
Italy
Biography
Prof. Meacci holds basic and advanced molecular biology courses for the Mat Fis and Nat Science School and for the Human Health School (former SMFN Faculty and Medicine and Surgery). Over the past 15 years, the topics of its research activity have been focused on the study of sphingolipids and in particular the signal transduction pathways induced by sphingosine 1-phosphate in various cell types, and the regulation of enzymes involved in the control of intracellular levels of these lipid mediators, such as sphingomyelinase, ceramidase, ceramide kinase and sphingosine kinase in muscle, heart and tumor cells. More recently, Prof Meacci's research has recruited the role of the 43-linked gap-cell junctions and stress-triggered channels (TRCPs) in the proliferation and myogenic differentiation of skeletal muscle stem cells.
Research Interest
Molecular Etiology
Publications
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Meacci, Elisabetta (2017). Crosstalk between sphingolipids and vitamin D3: potential role in the nervous system. Review.. BRITISH JOURNAL OF PHARMACOLOGY, vol. 174, pp. 605-627, ISSN:0007-1188
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Alessia, Frati; Mercedes, Garcia Gil; Federica, Pierucci; Elisabetta, Meacci (2017). Vitamin D and Sphingolipids: Role in Bone and Neural System.. In: Sivakumar Gowder (editor). A Critical Evaluation of Vitamin D - Basic Overview, pp. 129-160 Intech, ISBN:978-953-51-3083-3
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Pierucci F. ; Frati A. ; Squecco R. ; Lenci E. ; Vicenti C. ; Slavik J. ; Francini F. ; Machala M. ; Meacci E. (2017). Non-dioxin-like organic toxicant PCB153 alters Cx43-formed Gap junction function in liver progenitor cells through the modulation of sphingolipid metabolism .. ARCHIVES OF TOXICOLOGY, vol. 91, pp. 749-760, ISSN:0340-5761