Lisa Giovannelli
Associate professor
Department of Neuroscience, Area of ​​Pharmacy and Child
University of Florence
Italy
Biography
Lisa Giovannelli has attended the Degree in Biological Sciences at the University of Florence since 1979. She started working in the Department of Pharmacology as an internal student in 1982 and graduated in 1983 (Title of Thesis: "Effect of drugs nootropic on cerebral cholinergic mechanisms: biochemical and behavioral studies "). After graduating, he continued his research at the Department of Pharmacology, and in 1985 he entered the Doctoral Program in Pharmacology and Toxicology (4 years). During this period he has been carrying out research at The Scripps Research Institute, San Diego, CA, USA, Department of Neuropharmacology (1988-1990). In 1990 he obtained the Ph.D. in Pharmacology and Toxicology (Title of Thesis: " ), and continued working at Scripps as a post-doctoral fellow until he returned to Italy in 1991. From 1992 to 1994 she received a post-doctoral degree from MIUR (Title of the research line: "Study of the role of genes early in the recovery of cholinergic-induced NGF function in the magnocellular basal nucleus after injury "). In 1996 he became a researcher at the Faculty of Pharmacy of the University of Florence. In 1998 he obtained his degree in Clinical Biochemistry (title of thesis: "Using the comet test for DNA damage analysis in the central nervous system"). Since 2014 she is Associate Professor of the University of Florence, Department of Neuroscience, Psychology, Area of ​​Pharmacy and Child Health (NEUROFARBA). ), and continued working at Scripps as a post-doctoral fellow until he returned to Italy in 1991. From 1992 to 1994 she received a post-doctoral degree from MIUR (Title of the research line: "Study of the role of genes early in the recovery of cholinergic-induced NGF function in the magnocellular basal nucleus after injury "). In 1996 he became a researcher at the Faculty of Pharmacy of the University of Florence. In 1998 he obtained his degree in Clinical Biochemistry (title of thesis: "Using the comet test for DNA damage analysis in the central nervous system"). Since 2014 she is Associate Professor of the University of Florence, Department of Neuroscience, Psychology, Area of ​​Pharmacy and Child Health (NEUROFARBA). and continued his work at Scripps as a post-doctoral fellow until he returned to Italy in 1991. From 1992 to 1994 he obtained a post-doctoral degree from MIUR (Title of the research line: "Study of the role of early genes in recovery of cholinergic-induced NGF function in the magnocellular basal cell after injury "). In 1996 he became a researcher at the Faculty of Pharmacy of the University of Florence. In 1998 he obtained his degree in Clinical Biochemistry (title of thesis: "Using the comet test for DNA damage analysis in the central nervous system"). Since 2014 she is Associate Professor of the University of Florence, Department of Neuroscience, Psychology, Area of ​​Pharmacy and Child Health (NEUROFARBA). and continued his work at Scripps as a post-doctoral fellow until he returned to Italy in 1991. From 1992 to 1994 he obtained a post-doctoral degree from MIUR (Title of the research line: "Study of the role of early genes in recovery of cholinergic-induced NGF function in the magnocellular basal cell after injury "). In 1996 he became a researcher at the Faculty of Pharmacy of the University of Florence. In 1998 he obtained his degree in Clinical Biochemistry (title of thesis: "Using the comet test for DNA damage analysis in the central nervous system"). Since 2014 she is Associate Professor of the University of Florence, Department of Neuroscience, Psychology, Area of ​​Pharmacy and Child Health (NEUROFARBA). From 1992 to 1994 he obtained a post-doctoral degree from MIUR (Title of the research line: "Study of the role of early genes in the recovery of NGF-induced cholinergic function in the magnocellular baseline after injury"). In 1996 he became a researcher at the Faculty of Pharmacy of the University of Florence. In 1998 he obtained his degree in Clinical Biochemistry (title of thesis: "Using the comet test for DNA damage analysis in the central nervous system"). Since 2014 she is Associate Professor of the University of Florence, Department of Neuroscience, Psychology, Area of ​​Pharmacy and Child Health (NEUROFARBA). From 1992 to 1994 he obtained a post-doctoral degree from MIUR (Title of the research line: "Study of the role of early genes in the recovery of NGF-induced cholinergic function in the magnocellular baseline after injury"). In 1996 he became a researcher at the Faculty of Pharmacy of the University of Florence. In 1998 he obtained his degree in Clinical Biochemistry (title of thesis: "Using the comet test for DNA damage analysis in the central nervous system"). Since 2014 she is Associate Professor of the University of Florence, Department of Neuroscience, Psychology, Area of ​​Pharmacy and Child Health (NEUROFARBA). Publications in peer reviewed journals with IF: 67 Total Citations (Scopus): 2824 Publications 2010-2015 in peer reviewed journals with IF: 12 H-index: 29 (Scopus) G-Index: 52 (calculated from Scopus data) E 'author of 11 chapters of internationally-disseminated books. His research activity is documented by his participation in more than 50 national and international congresses. The main research interests are in the field of degenerative diseases and aging. SCIENTIFIC EXPERIENCE 1983-1988 Department of Pharmacology, Florence. Dr. Giancarlo Pepeu. Experimental research on cerebral aging in relation to cholinergic, purinergic and calcium flows: in vivo and in vitro methods. 1988-1991 Department of Neuropharmacology, the Scripps Research Institute, San Diego, CA, USA. Dr. Floyd E. Bloom. The expression of early genes as a neuronal activation marker: immunohistochemical studies and molecular biology. 1991-1996 Department of Pharmacology, Florence. Dr. Giancarlo Pepeu. Toxicity of beta-amyloid peptides in in vivo models of Alzheimer's disease. 1996-present Department of Pharmacology until 2011, then Department of Neuroscience, Psychology, Area of ​​Medication and Child Health (NEUROFARBA), Florence. Damage to DNA as a marker of environmental pollutants, degenerative diseases and aging: studies in experimental models and in humans. Protective effects of natural antioxidants in aging: functional and biochemical studies in humans, in laboratory animals and in cell cultures. Membership in scientific societies 1990-98 Society for Neuroscience, USA 1996- Italian Society of Pharmacology 2004- Network of Excellence NuGO (European Nutrigenomics Organization, www.nugo.org) 2008- Italian Society of Toxicology 2011- Groupe Polyphenols (www.groupepolyphenols. com) Membership in Professional Albi Since 1993 he has been a member of the National Biologists' Order, and has moved to the Special Biology List since September 1996. Other scientific activities He has been a referee for the journals: Neuroscience Letters, Journal of Neurochemistry, European Journal of Nutrition, Clinical Nutrition, Nutrition and Metabolism, Journal of the Science of Food and Agriculture, Rejuvenation Research, Age. DEGREE ACTIVITY Teaching of Teaching 2000 PhD in Chemistry and Pharmaceutical Technology: Dermopharmacology-30 hours 2002-2012 Three Year Degree in Biotechnology - Pharmaceutical Address: Toxicology-6 CFU Lending Courses: 2008-2009 Three Year Degrees in Environmental Toxicology, Herbal Techniques and Scientific Information on Drugs: Toxicology 2010-2011 Three Year Degree in Applied Pharmaceutical Sciences: Toxicology 2007-2009 Specialized Degree in Pharmaceutical Biotechnology: Cellular and Molecular Pharmacology (co-holder ) -3 CFU 2010 Bachelor's Degree in Applied Pharmaceutical Sciences: Pharmacovigilance-3 CFU 2010-2011 Pharmacy Specialist in Pharmacy: Clinical Pharmacy (activities chosen by the student) -4 CFU 2012-now Master's Degree in Pharmacy: Toxicology-6 CFU 2013- today Master's Degree in Pharmacy: Pharmacovigilance and Pharmacodepidemiology (co-holder) -3 CFU Doctoral thesis and doctoral thesis From 1996 to present he has been a Ph.D. Pharmacology, Toxicology, Pharmacovigilance and Fitovigilance PhD student at the Faculty of Pharmacy / School of Human Health Sciences: Rapporteur (35 experimental and 6 compilative) co-rapporteur (6 experimental and 5 compilative) of the Faculty of Mathematical, Physical and Natural Sciences (Bachelor of Science in Biological Sciences) rapporteur (3 experimental). Scientific Director and Speaker of PhD thesis in Pharmacology and Toxicology XXIII cycle, titled "Anti-inflammatory and anti-aging activity of plant-based phenols: in vitro and in vivo models". Scientific Director of a Ph.D. of the XXXI cycle. Postgraduate courses - Lecturer in the training event "Nutritional Supplements: Lights and Shadows" organized by the Company USL 8, Annual Training Plan 2010 for Doctors, Arezzo 22/05/2010. - Professor in the professional form of the Tuscany Region: "Expert in Dermopharmacology", 2006. - Dermopharmacologic lessons for the School of Specialization in Hospital Pharmacy in Florence, AA 2005-2006. - Professor at the "Dermatological Affective Therapy" course (n ° 3286-195005) organized by the Provincial Order of Pharmacists of Pistoia, 2004. INSTITUTIONAL INCENTIVES AND ROLES 2005 representative of the Faculty of Pharmacy before the Board and then the Committee for the Didactics of Biotechnology Interfaculty Degree Program. 2007-2011 Delegate to the orientation and tutorship of the degree program in Scientific Information on the Applied Pharmaceutical / Applied Pharmaceutical Sciences. 2008-2012 Component of the Committee for the Teaching of the Degree in Applied Pharmaceutical Sciences. 2008-2013 Component of the GAV (Self-Assessment Group) of the Bachelor's Degree in Applied Pharmaceutical Sciences. 2009 Member of the Commission for State Examinations for Professional Exercise for Pharmacists, 1st and 2nd Session. 2010 Representative of the Faculty of Pharmacy in the Interface Coordination on DDL 1905 on "Organization and quality of the university system, academic staff and the right to study". 2013-present Component of the Commission of Pharmacy Degree Course. 2015 Member of the Commission for State Examinations for Professional Exercise for Pharmacists, 1st and 2nd Session. 2008 and 2009 Member of the PhD School of Pharmacology and Toxicology College. 2010 and 2011 Member of the Doctoral School of PhD School of Pharmacology, Toxicology and Innovative Treatments (International). 2012-2014 Member of the Doctoral School of PhD School of Medicine and Innovative Treatments (International). Member of Judicial Admission Committee for Research Phase and Competition for Research Grants, Fellowships, Scholarships and Co.Co.Co. 2014 Component designated by the University of Florence of the Complementary Medicine Training Commission of the Tuscany Region. SCIENTIFIC PARTICIPATION IN NATIONAL AND INTERNATIONAL RESEARCH PROJECTS, Admitted to funding on the basis of competitive calls for peer review - EU COST Action hComet - OC-2015-1-19739: The comet assay as a human biomonitoring tool. Duration: 48 months. Role: Head of Operations Unit. - Toscano Tumori Institute 2008 - Oxidative damage and mutation frequency in somatic cells: correlation in healthy subjects and in patients with head and neck cancer. Duration: 24 months. Role: Head of Operations Unit. - EU project FLAVO - FOOD-CT-2005-513960: Flavonoids and Health. Duration: 36 months. Role: Head of Operations Unit. - EU project POLYBIND - QLK1-CT-1999-00505: Health implications of natural non-nutrient antioxidants (polyphenols); bioavailability and colon carcinogenesis. Duration: 36 months. Role: Participant. - EU project ESCODD - QLK1-1999-00568: European Standards Committee on oxidative DNA Damage. Duration: 36 months. Role: Head of Operations Unit. - EU Network of Excellence NUGO (FOOD-CT-2004-506360). Duration: 72 months. Role: Participant. Other funding: - Savings Bank of Florence 2012. Title: Anti-aging effect of polyphenols of extra virgin olive oil. Duration: 12 months. Role: Research Manager. - S. Pitigliani Foundation for the Fight against Tumors, Prato 2010. Title: Early screening of breast cancer subtypes susceptible to genotoxic chemotherapy by using the comet assay. Duration: 24 months. Role: Research Manager.
Research Interest
Pharmacology
Publications
-
V. Pitozzi; M. Jacomelli; D. Catelan; M. Servili; A. Taticchi; A. Biggeri; P. Dolara; L. Giovannelli (2012). Long-term dietary extra-virgin olive oil rich in polyphenols reverses age-related dysfunctions in motor coordination and contextual memory in mice: role of oxidative stress. REJUVENATION RESEARCH, vol. 15 (6), pp. 601-612, ISSN: 1549-1684
-
Lisa Giovannelli; Marzia Innocenti; Anna Rita Santamaria; Elisabetta Bigagli; Gabriella Pasqua; Nadia Mulinacci (2014). Antitumoral activity of viniferin-enriched extracts from Vitis vinifera l. cell cultures. NATURAL PRODUCT RESEARCH, vol. 28, pp. 2006-2016, ISSN: 1478-6419
-
Piroddi, Marta; Albini, Adriana; Fabiani, Roberto; Giovannelli, Lisa; Luceri, Cristina; Natella, Fausta; Rosignoli, Patrizia; Rossi, Teresa; Taticchi, Agnese; Servili, Maurizio; Galli, Francesco (2016). Nutrigenomics of extra-virgin olive oil: A review. BIOFACTORS, vol. -, pp. 1-25, ISSN: 0951-6433
-
ascarella, Simona; Tiberi, Caterina; Sabatino, Giuseppina; Nuti, Francesca; Papini, Anna Maria; Giovannelli, Lisa; Rovero, Paolo (2016). Serpin A1 C-Terminal Peptides as Collagen Turnover Modulators. CHEMMEDCHEM, vol. ..., pp. n / an / a, ISSN: 1860-7179
-
Menicacci, B; Laurenzana, A; Chillà , A; Margheri, F; Peppicelli, S; Tanganelli, E; Fibbi, G; Giovannelli, L; Del Rosso, M; Mocali, A. (2017). Chronic resveratrol treatment inhibits MRC5 fibroblast SASP-related pro-tumoral effects on melanoma cells. JOURNAL OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, p. 0-0, ISSN: 1079-5006