Marzia Innocenti

Biography

Department of NEUROFARBA, Division of Pharmaceutical Sciences and Nutrition, via U. Schiff 6 9, 50019, Sesto Fiorentino- Florence, Italy. Tel. ++ 39-055-4573778; Fax ++ 39-055-4573737; E-mail marzia.innocenti@unifi.it 2012. Full-time researcher at SSD CHIM-10 Confirmed since 12/05/20012 2011 . Aggregate Professor 2009. University Researcher CHIM-10 2004. Ph.D. in Pharmaceutical Chemistry and Technology . Thesis on "Herbal medicines and nutritional supplements" 2000. Enable the Pharmacist's work 1992-2000 . Graduation thesis with 110/110 votes and praise in Pharmaceutical Chemistry and Technology at the University of Florence. Title of thesis "Cicoria ( Cichorium intybus L.) as a source of polyphenols: caffeoil derivatives and flavonoids" 1987-92. High school diploma at Liceo P. Gobetti (scientific high school) Teaching activity - Dr. Marzia Innocenti has held a series of lessons under the Food Chemistry Course within the Master Interfaculty in "Food Quality and Wellbeing" held in Florence during the following periods: January 2003, January 2004, February 2005 - In the AA 2004-2005 he held an 8-hour class module within the Chemistry of Food courses at the 3rd year of the Pharmacy Specialist Degree Course, University of Florence - In the academic year 2004-2005 he has been engaged in collaboration to hold 15 hours of Teaching within the module Professionalizzante "Technical Expert of Medicinal Herbs " activated as part of the degree course in Herbal Techniques. Within the same professional training module he held 55 hours of tutoring for students . In 2005 he held , for the Order of Pharmacists of Florence, a lecture entitled "Dietary supplements in sport" carried out as part of the course UPDATES- ECM, entitled "Dietary supplements in sport and obesity." In AA 2005-2006 he has been awarded the Collaboration to hold 8 hours of Assisted Learning Activities for the Food Chemistry module under the Professional Expertise in Quality Management Systems in the Food Sector: 2nd Assessment and Audit IFS and BRC standards ". In the AA 2005-2006 he held a 8-hour class module in the Chemistry of Foods at the 3rd year of the Pharmacy Degree Course in the University of Florence (see Annex 3) . In AAB 2006-2007 he held a 8-hour class module in the Chemistry of Foods at the 3rd year of the Pharmacy Degree Course in the University of Florence (see Annex 3) . In November 2006 Viareggio held seminars on Food Chemistry under the "Quality and Food Safety" Project. These seminars, organized in collaboration between CeRA (Centro Ricerche Alimenti) and the Tuscany region, were aimed at catering operators. In AAR 2007-2008 he held an 8-hour class module in the Chemistry of Foods at the 3rd year of the Pharmacy Specialist Degree Course, University of Florence In the academic year AA 2010/2011 he held a 16-hour (2 CFU) module in the course of Food Chemistry for Applied Pharmaceutical Sciences Course-CQ During the academic year AA 2011/2012 he held a 16-hour (2 CFU) module in the course of Food Chemistry for Applied Pharmaceutical Sciences Course-CQ In relation to the academic year 2010/2011, it received an incentive for research funds based on the didactic activity given to researchers Since 2004 he has been attending several graduates in the field of experimental or compilation theses for Pharmacy degree in Pharmaceutical Chemistry and Technology as listed below and in Biotechnology and has been correlative of 13 experimental theses and 5 compilative theses: Experimental theses 1. Thesis of Specialized Degree in Chemistry and Pharmaceutical Technology under the title "Rosa L canine: qualitative quantitative phytochemical characterization of the main components in selected cultivars", October 2002. 2 . PhD thesis in Chemistry and Pharmaceutical Technology by title "Valuation of solid waste pulp (sanse) as a source of bioactive phenylpropanoids", December 2003. 3. Pharmacy PhD thesis entitled "Carotenoids, Vitamin C and Phenolic Compounds in False Cuttings and Leafs Selected by Rosa Canina L." February 2004. 4 . PhD thesis in Chemistry and Pharmaceutical Technology by title "Phenylpropanoids and secoiridoids from crushed oil: isolation and structural characterization", October 2005. 5 . PhD thesis in Chemistry and Pharmaceutical Technology by title " Verbascoside and derivatives: from drugs to cosmetic preformulation", March 2006. 6 . PhD thesis in Pharmacy: "Production of trans-resveratrol and other cell culture cultures of Vitis vinifera L.: quantitative analysis by HPLC / DAD and HPLC / MS / MS", April 2007. 7 . PhD thesis in Pharmacy: "From Cheese Fodder: Is it possible to identify phytochemical markers useful for traceability? April 2008. 8 Experimental Thesis in Pharmacy Pharmacy with the title: "Study on bioactive components of edible fruits of Brazilian plants for the enhancement of biodiversity: Annona crassiflora Mart. and Butia capitata Mart. from the Cerrado area ". May 2010 9 . Experimental Thesis of Degree Specialized in Pharmacy with the title: "Production of stilbenes from cell cultures of Vitis vinifera L. and vinification waste: chemical characterization and evaluation of biological activities of extracts enriched in viniferine", October 2010. 10. Experimental Thesis in Pharmacy Pharmacy with the title: " Vitis vinifera L cellular cultured stylibenes : biosynthesis, extraction and evaluation of antitumor and antimycotic activity", April 2011. 11. PhD thesis in Chemistry and Pharmaceutical Technology entitled "Amyloid Aggregation: A Methodological Approach to Defining Potential and Limitations of Survey Techniques for Phenolic Inhibitor Study on Model Systems" April 2012. 12. PhD thesis in biotechnology Pharmacy address entitled "Viniferine from cell cultures of Vitis vinifera L.: extraction, isolation, chemical characterization and evaluation of antitumor activity". April 2012 13. Experimental Thesis of Pharmacy Specialist Degree entitled: "Extraction of bioactive phenols from" green berries "and other scraps of the viticultural chain and evaluation of antifungal activity. June 2012. Compilation thesis 1st Pharmacy Pharmacy Thesis titled "Celiac Products: Composition, Nutrition and New Raw Materials", April 2010. 2. Pharmacy Pharmacy degree titled "Supplements for weight control in pharmacy". May 2010 3. Pharmacy Pharmacy Thesis titled "Phenols in Plant Foods and Their Positive Impact on Human Microbiotics", October 2011. 4. Pharmacy Pharmacy Thesis titled " Monascus purpureus : A component of cholesterol control supplements", December 2011. 5. Ph.D. thesis on "Coffee: recent scientific acquisitions and effects on human health of an old drink". March 2012. From 2004 to 2012 he has also been a member of a number of Degree Courses of Pharmacology and Food Testing Commissions for the Course of Food Chemistry, in the following Degree Programs: Pharmacy Degree, Bachelor Program in Herbal Techniques, Course of Degree in Environmental Toxicology, Degree in Quality Control, Degree in Biotechnology at the University of Florence Scientific activity From 2000 to present he has conducted his scientific research at the Department of Pharmaceutical Sciences of the University of Florence, dealing mainly with the development of specific methods of extraction, fractionation, isolation and characterization of secondary metabolites from food and / or medicinal plants, potential interest in the pharmaceutical, food and cosmetic sectors. He has participated in various national and international congresses (total 11) presenting oral and postal communications ( 43 in total ). He has attended several Italian and foreign schools and seminars (in total 34). Research conducted from 2000 to date has led to the development of scientific collaborations with Italian and foreign universities , with research centers (cnr) and small and medium-sized enterprises mainly in the agro-food sector. These activities have taken place in several conferences with related presentations of oral and posters and have led to the publication of 30 papers in international journals (see list of publications) MAIN RESEARCH LINES FROM 2000 ONWARDS: - Study of the quantum profile of phenols, flavonoids, anthocyanins, secoiridoids, carotenoids, iridoids, saponins in species of agri-food interest such as Vitis vinifera L. (leaves, fruits, wines), Olea europea L. (leaves, olives, oil, sanse, and sewage), Oriza sativa L. (rice) dark pigment varieties, Chicorium intibus L. (aerial parts), pigmented varieties of Solanum tuberosum L.; in officinal plants such as L., Rosa canina . L., Juniperus communis L. , Tribulus terrestris L., Verbena officinalis L., Lippia citrodora L., - optimization of extraction and fine-tuning of quantitative-quantitative analyzes mainly via HPLC / DAD / MS of bioactive molecules from waste matrices in the agro-food sector such as oil reflux and sanitation by the extra virgin olive oil chain; wineskin from winemaking processes; pruning cake of Mediterranean blot species, artichoke waste for the production of standardized high quality organic extracts that can be used as dietary supplements and / or in the pharmaceutical or cosmetic field. - Development and optimization of extractive and analytical methods predominantly directed to the characterization of polar compounds of extra-virgin olive oils of various origin. In particular, they were determined in a number of minor polar compounds samples such as thiosulph, OH - thiol, secoiridoids, flavonoids, lignans, etc. - Research on secondary metabolites produced by cell cultures of higher plants. In particular, a quantitative study was carried out on the biotransformation of exogenous substrates such as apigenine, lutein, biocanine, taxifoline, hemodine and aloemodine by Ajuga reptans L cell cultures. Subsequently a study was started, University of La Sapienza in Rome, on secondary metabolites such as anthocyanins obtained from cultured cell cultures of acuminated Campthoteca and Vitis vinifera L. cell cultures of stilbenoids subjected to various eliciting systems to modulate and increase the production of such molecules. - Structural characterization of compounds isolated from biological interest matrices by analysis in MS and / or MS / MS and Nuclear Magnetic Resonance experiments both mono and two-dimensional (1D- and 2D-NMR). - Optimization of extractive and analytical methods for the identification and recovery of phytochemical markers, in particular phenolic compounds, from matrices such as forage, milk, whey and pecorino cheese from two Tuscan areas. - Study of the qualitative profile of the bioactive components present in dyes based on plant extracts and gammo derivatives for the quality control of such preparations: the development of analytical methods suitable for the simultaneous monitoring of secondary metabolites belonging to different chemical classes ; stability study over time.

Research Interest

Food Chemistry