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Monica Bucciantini

Associate Professor
Department of Biomedical, Experimental and Clinical Sciences
University of Florence
Italy

Biography

Dr. Monica Bucciantini, born in Pistoia on 17/08/1964, since April 1990 has attended the Department of Biochemical Sciences of the University of Florence as an internal student and then as a fellow, specialist, doctorate and assignor, collaborating with research group Prof. G. Ramponi in conducting research on two phosphomonoidrolases. On 13/9/1991 he graduated in Biological Sciences with a vote of 110/110 discussing a thesis titled "Expression and turnover of muscle inzulin of acylphosphatase in myoblasts L6". In December 1992 he obtained the qualification for Biologist profession by supporting his state examination and enrolled in the School of Specialization in Biochemistry and Clinical Chemistry at the Faculty of Medicine and Surgery of the University of Florence, its diploma on 31/10/1996. In September 1992 he was the winner of a CNR scholarship for research in the project "Biotechnology and Biostructure", working on a research project on the structure-function relationships of acylphosphatase by using a site-specific mutagenesis approach and with subsequent enzymatic activity evaluations and structural analysis by NMR spectroscopy. In November 1993 he participated in the course "Peptides as synthetic antigens and immunogens" organized by the UETP-Tuscany Consortium and the Department of Molecular Biology at the University of Siena. For the year 1993, the CNR Stock Exchange has been reconfirmed for carrying out a research on the synthesis of antisense peptides. In 1995, as a winner of a Lincei Academy's Stock Exchange, he undertook a research project aimed at the determination of the physiological substrate of a low molecular weight phosphatase phosphatase phosphatase. Since 1995, Dr. Monica Bucciantini has collaborated with the Department of Molecular Biology at the University of Stockholm, where she went for three months, from March to June 1995, dealing with protein crystallization methods and carrying out structural studies of said phosphotyrosine protein phosphatase by X-ray crystallography. He participated in the Computational Chemistry Course organized by the University of Siena held in Pontignano (SI) on June 10-15, 1996. For the years 1996-1998 Dr. Monica Bucciantini benefited from a stock exchange A.I.R.C. for a research project on the role of low molecular weight PTPase in cell differentiation and proliferation processes.

Research Interest

Biochemistry

Publications

  • M. Leri; D. Nosi; A. Natalello; R. Porcari; M. Ramazzotti; F. Chiti; V. Bellotti; S.M. Doglia; M. Stefani; M. Bucciantini (2016). The polyphenol Oleuropein aglycone hinders the growth of toxic transthyretin amyloid assemblies. JOURNAL OF NUTRITIONAL BIOCHEMISTRY, vol. 30, pp. 153-166, ISSN:0955-2863

  • Mercatelli, R ; Lana, D; Bucciantini, M; Giovannini, MG; Cerbai, F; Quercioli, F; Zecchi-Orlandini, S; Delfino, G; Wenk, G; Nosi, D (2016). Clasmatodendrosis and β-amyloidosis in Aging Hippocampus. FASEB JOURNAL, vol. 30, pp. 1480-1491, ISSN:0892-6638

  • Raimondi, S.; Pp, Porcari R.; Mangione .; Verona, G.; S, Marcoux J.; Giorgetti .; Taylor, Gw.; Ellmerich, S.; Ballico, M.; Zanini, S.; Pardon, E.; Al-Shawi, R.; Simons, Jp.; Corazza, A.; Fogolari, F.; Leri, M.; Stefani, M.; Bucciantini, M.; Gillmore, Jd.; Hawkins, P.N.; Valli, M.; Stoppini, M.; Robinson, Cv.; Steyaert, J.; Esposito, G; Bellotti, V (2017). A specific nanobody prevents amyloidogenesis of D76N β2-microglobulin in vitro and modifies its tissue distribution in vivo. SCIENTIFIC REPORTS, vol. 7, pp. 46711-46722, ISSN:2045-2322

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