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Paolo Calabresi

Associate Professor
Department of Internal Medicine
University of Perugia
Italy

Biography

 Paolo alabresi granted his  Degree in Medicine and Surgery, University “La Sapienza”, Rome and Specialization in Neurology, University “La Sapienza”, Rome: Post-doctoral fellow at the Max Planck Institut (Dept. Neurophysiology, Director Prof. H. D. Lux), Munich, Germany, Post-doctoral fellow at the Oregon Health Science University – Vollum Institute – Lab. Neuropharmacology Portland (Oregon), U. S. A. He worked as Assistant Professor in Neurology – University Tor Vergata, Rome, Italy: Professor of Neurophysiology and Neuropharmacology at the School of Neurology - University Tor Vergata, Rome, Italy: Co-ordinator of the Clinical Group for the Study of the Movement Disorders at the Sant’Eugenio Hospital – University Tor Vergata, Rome, Italy: Associate Professor in Neurology – University Tor Vergata, Rome, Italy and  from 2005 - present: Full Professor of Neurology and Chairman of Neurology at the University of Perugia, Italy.

Research Interest

 synaptic communication between the cerebral cortex and the basal ganglia, focussing on corticostriatal synapses and their activity-dependent plasticity

Publications

  • Calabresi P, Picconi B, Tozzi A, Ghiglieri V, Di Filippo M. Direct and indirect pathways of basal ganglia: a critical reappraisal. Nature neuroscience. 2014 Aug 1;17(8):1022-30.

  • Tozzi A, de Iure A, Bagetta V, Tantucci M, Durante V, Quiroga-Varela A, Costa C, Di Filippo M, Ghiglieri V, Latagliata EC, Wegrzynowicz M. Alpha-synuclein produces early behavioral alterations via striatal cholinergic synaptic dysfunction by interacting with GluN2D N-methyl-D-aspartate receptor subunit. Biological psychiatry. 2016 Mar 1;79(5):402-14.

  • Calabresi P, Pisani A, Rothwell J, Ghiglieri V, Obeso JA, Picconi B. Hyperkinetic disorders and loss of synaptic downscaling. Nature neuroscience. 2016 Jul 1;19(7):868-75.

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