Exhibition Carla

Biography

Prof. Carla Esposito was born in Naples on 19.6.1951. He graduated from the Faculty of Pharmacy of the University of Naples in 1975. In 1980 he passed the qualification test for confirmed researcher (E05A) in the first round. In 1999 he was the winner of a 2nd place band for the disciplinary field E05A (Biochemistry). Since 2004 he has been a professor of Biological Chemistry at the Faculty of Physical and Natural Sciences of the University of Salerno. From 1980 onwards he has been assigned numerous teaching assignments at the Faculty of Medicine and Surgery and at the Agrarian Faculty of the University of Naples, at the University of Salerno. He has conducted scientific research at the Department of Biochemistry and Biophysics at the University of Naples, the Department of Chemistry at the University of Salerno and the Mental Health Research Institute of the University of Michigan (Ann Arbor, USA). Author of more than 70 publications on specialized international journals. The main topics addressed are: Purification and characterization of polyamine biosynthesis enzymes; Role of secreted proteins from seminal vesicles. Transglutamination reactions: a) effects on membrane enzymes; b) role in spermatozoa maturing process; c) possible implications in the suppression of the antigenic characteristics of spermatozoa; d) role in mitogen-induced lymphocyte proliferation; e) determination of reaction products; f) use of transglutaminase to modify the biological structure and activity of peptides and proteins; g) purification and characterization of rat prostate transglutaminase; h) synthesis using the transglutaminase enzyme of P agonists and antagonists; (i) role in the etiopathogenesis of pathologies such as celiac disease and neurodegenerative diseases.

Research Interest

Purification and characterization of polyamine biosynthesis enzymes; Role of secreted proteins from seminal vesicles. Transglutamination reactions: a) effects on membrane enzymes; b) role in spermatozoa maturing process; c) possible implications in the suppression of the antigenic characteristics of spermatozoa; d) role in mitogen-induced lymphocyte proliferation; e) determination of reaction products; f) use of transglutaminase to modify the biological structure and activity of peptides and proteins; g) purification and characterization of rat prostate transglutaminase; h) synthesis using the transglutaminase enzyme of P agonists and antagonists; (i) role in the etiopathogenesis of pathologies such as celiac disease and neurodegenerative diseases.