Gabriella Marisa Leonarduzzi
Department of Clinical and Biological Sciences
University of Turin
Italy
Biography
Gabriella Marisa Leonarduzzi is an Associate professor of general pathology at the Department of Department of Clinical and Biological Sciences ,University of Torino, Italy.
Research Interest
Experimental studies on several therapeutic strategies to counteract cell damage during the development of atherosclerosis and Alzheimer's disease (AD) ; Modulation of signaling transduction pathways and target genes by oxidized lipids in the pathogenesis of these diseases; Age-related human diseases associated with oxidative stress and inflammatory response, in particular atherosclerosis and Alzheimer's disease (AD).
Publications
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Gamba P, Leonarduzzi G, Tamagno E, Guglielmotto M, Testa G, Sottero B, Gargiulo S, Biasi F, Mauro A, Vina J, Poli G. Interaction between 24â€hydroxycholesterol, oxidative stress, and amyloidâ€Î² in amplifying neuronal damage in Alzheimer’s disease: three partners in crime. Aging cell. 2011 Jun 1;10(3):403-17.
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Gargiulo S, Sottero B, Gamba P, Chiarpotto E, Poli G, Leonarduzzi G. Plaque oxysterols induce unbalanced up-regulation of matrix metalloproteinase-9 in macrophagic cells through redox-sensitive signaling pathways: Implications regarding the vulnerability of atherosclerotic lesions. Free Radical Biology and Medicine. 2011 Aug 15;51(4):844-55.
