Paola Francesca Gamba
Department of Clinical and Biological Sciences
University of Turin
Italy
Biography
Paola Francesca Gamba is a Researcher of general pathology at the Department of Clinical and Biological Sciences ,University of Torino, Italy.
Research Interest
The research focuses on the role of oxidized lipids, particularly cholesterol oxidation products, known as oxysterols, and 4-hydroxynonenal (HNE) in age-related chronic diseases, with emphasis on atherosclerosis and Alzheimer's disease (AD).
Publications
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Gamba P, Leonarduzzi G, Tamagno E, Guglielmotto M, Testa G, Sottero B, Gargiulo S, Biasi F, Mauro A, Vina J, Poli G. Interaction between 24â€hydroxycholesterol, oxidative stress, and amyloidâ€Î² in amplifying neuronal damage in Alzheimer’s disease: three partners in crime. Aging cell. 2011 Jun 1;10(3):403-17.
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Gargiulo S, Sottero B, Gamba P, Chiarpotto E, Poli G, Leonarduzzi G. Plaque oxysterols induce unbalanced up-regulation of matrix metalloproteinase-9 in macrophagic cells through redox-sensitive signaling pathways: Implications regarding the vulnerability of atherosclerotic lesions. Free Radical Biology and Medicine. 2011 Aug 15;51(4):844-55.
