But Bonis Michele

Biography

PERSONAL INFORMATIONS Name and titles: MICHELE DE BONIS, MD, FESC, FAHA Place of birth: Pietragalla (Potenza) - Italy Date of birth: July 29, 1968 Italian nationality. Languages ​​spoken: Italian, English, French. Domicile: Via Michelangelo Buonarroti 41 20063 Cernusco sul Naviglio; Milan, Italy Phone: + 39-02 9231560 Mobile: +39 335 8418152 Work: University of "Life and Health" San Raffaele Division of Cardiac Surgery San Raffaele Hospital Via Olgettina 60, 20132 Milan, Italy Phone: + 39-02-2643 7118 Fax: + 39-02-2643 7125 Email: debonis.michele@hsr.it PROFESSIONAL EXPERIENCE - Professor of the band for the competition sector 06 / E1 - Cardio-Toraco-Vascular Surgery, SSD MED / 23 - Cardiac Surgery at the Faculty of Medicine and Surgery of San Raffaele University of Milan. Teaching activities at the Degree Course in Medicine and Surgery, the Nursing Degree Course and the School of Specialization in Cardiac Surgery (from 2016 to the present date). - Elected Director of the School of Specialization in Cardiac Surgery, Faculty of Medicine and Surgery of the San Raffaele Health and Life University of Milan (2017) - Visiting Professor of Cardiac Surgery at Plymouth NHS Trust, Plymouth, United Kingdom (since 2017) - Visiting Professor of Cardiac Surgery at the Cardiovascular Research Unit, Faculty of Health Sciences, University of Cape Town, South Africa (from 2017) - Head of Cardiac Surgery Functional Unit (Clinical and Research Activity) - Cardio Surgery Unit - San Raffaele University Hospital, Via Olgettina 60, 20132 Milan, Italy (2009 to present date). - Professor in the disciplinary disciplinary field MED / 23 - Cardiac Surgery of the Specialized Degree Course in Medicine and Surgery at the Faculty of Medicine and Surgery of the San Raffaele Health and Life University of Milan (2008 to 2016) - Professor at the School of Specialization in Cardiac Surgery of the San Raffaele University of Life and Health University of Milan (2007-2016) - Professor of Medical discipline MED / 23 - Cardiac Surgery of the Degree Course in Nursing, under the Integrated Course under C.14 Clinical Nursing in Specialist Surgery, Faculty of Medicine and Surgery of the Vita-Salute University San Raffaele of Milan (2007-2016) - Senior Medical Manager (Clinical and Research Activities), Cardio Surgery Unit, San Raffaele University Hospital, Milan, Italy (2007-2008) - Medical Manager I Level (Clinical and Research Activity). Cardiac Surgery Unit, San Raffaele University Hospital, Milan, Italy (2000-2006) Clinical Responsibility Wide experience as the first operator in the surgical treatment of all adult heart disease. Mitral and tricuspid valve rehabilitation surgery and the circular support (ECMO, LVAD, BiVAD, TAH) represent areas of specialization. Mini-invasive and trans-catheter valve surgery, and aortic valve repair surgery are the current areas of most clinical and scientific interest. Since 2009 she has been appointed Head of the Cardiac Surgery Functional Unit (Clinical and Research Activity) of the Cardiac Surgery Unit of the San Raffaele University Hospital in Milan. In this way, she has gained a solid experience in surgical treatment of patients with heart failure. He is also responsible for the divisional division of Sickness Surgery for over 15 years of preoperative evaluation and follow up of these patients together with a group of collaborators dedicated to this project. After a period of training as a Fellow on Circulation Mechanisms at the German Heart Institute in Berlin, he started close collaboration with the Cardiac Surgery Intensive Care Unit, a comprehensive program of mechanical support at the Circle at the San Raffaele Hospital in Milan. This program is currently consolidated and includes the use of paracorporei systems (veno-arterial and veno-venous ECMO, LVAD / RVAD / BiVAD type CentriMag-Levitronix), partially implantable systems (Incor, Jarvik, HeartMate II, HeartMate III, Heartware) and Cardiowest total artificial heart. Currently about 120 patients / year are subjected to veno-venous / veno-arterial ECMO implantation and about 100 patients received an LVAD as an alternative to target therapy. "Destination therapy" represents a specific field of clinical, surgical and research interest. Since 2015 she has been acting as a "proctor" for the installation of left ventricular system HeartMate II and HeartMate III. He has obtained the following certifications for the SynCardia TAH implantation and the left HeartMate III left ventricular system: SynCardia Total artificial heart phase I training Germany 24th February 2012 HeartMate III Masterclass National Research Cardiac Surgery Center Astana, Kazakhstan June 30th-July 1st 2015 Other national and international roles and assignments Over the years, he has had important national and international roles in the European Association for Cardiothoracic Surgery (EACTS), the European Society of Cardiology (ESC), the American Heart Association (AHA) and the Italian Society of Cardiac Surgery (SICCH) and the Heart Valve Society (HVS). The intense organizational and scientific activity has enabled him to obtain the Fellowship of the European Society of Cardiology (FAES) and the American Heart Association (FAHA) and to reach positions also within these organizations such as: - Chairship of the Working Group on Cardiovascular Surgery of the European Society of Cardiology (2014-2016). - the role of "liaison" for Europe of the Leadership Committee of the Council on Cardiovascular Surgery and Anesthesia of the American Heart Association (2015 current date). He has also been the coordinator of the "Committee for Guidelines and Position Papers" and member of the Italian Society of Cardiac Surgery (2014-2016), a member of the "Committee for the Relations with the European Association for Cardiothoracic Surgery" Within these companies (ESC, EACTS, AHA, HVS) has systematically participated in the organization of related congressional scientific programs as a member of its "Congress Program Committes" (CPC), elaborating proposals for the various sessions and selecting and finalizing them during their respective CPC Meetings. Guidelines of European Society of Cardiology and Cardiac Surgery He was a member of "The Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardiovascular Surgery (EACTS) (version 2012) and participated in the drafting of the following European guidelines on valvulopathies and infectious endocarditis: 1) Authors / Task Force Members, Vahanian A, Alfieri O, Andreotti F, Antunes MJ, Baron-Esquivias G, Baumgartner H, Borger MA, Carrel TP, De Bonis M, Evangelista A, Falk V, Iung B, Lancellotti P, Pierard L, Price S, Schäfers HJ, Schuler G, Stepinska J, Swedberg K, Takkenberg J, Von Oppell UO, Windecker S, Zamorano JL, Zembala M; ESC Committee for Practice Guidelines (CPG), Bax JJ, Baumgartner H, Ceconi C, Dean V, Deaton C, Fagard R, Funck-Brentano C, Hasdai D, Hoes A, Kirchhof P, Knut J, Kolh P, McDonagh T, Moulin C, Popescu BA, Reiner Z, Sechtem U, Sirnes PA, Tendera M, Torbicki A, Vahanian A, Windecker S; Document Reviewers: Popescu BA, Von Segesser L, Badano LP, Bunc M, Claeys MJ, Drinkovic N, Filippatos G, Habib G, Kappetein AP, Kassab R, Lip GY, Moat N, Nickenig G, Square N, Pieper PG, Rosenhek R, Shuka N, Schwammenthal E, Schwitter J, Mas PT, Trindade PT, Walther T. The Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardiac Thoracic Surgery (EACTS). Eur Heart J. 2012 Oct; 33 (19): 2451-96 2) 2015 ESC Guidelines for the Management of Infectious Endocarditis: The European Association of Nuclear Medicine (EACTS), European Association for Cardiovascular Surgery (EACTS), European Association for Cardiovascular Surgery (EANM). Authors / Task Force Members, Habib G, Lancellotti P, Antunes MJ, Bongiorni MG, Casalta JP, Del Zotti F, Dulgheru R, El Khoury G, Erba PA, Iung B, Miro JM, Mulder BJ, Plonska-Gosciniak E, Price S, Roos-Hesselink J, Snygg-Martin U, Thuny F, Tornos Mas P, Vilacosta I, Zamorano JL; Document Reviewers, Erol Ç, Nihoyannopoulos P, Aboyans V, Agewall S, Athanassopoulos G, Aytekin S, Benzer W, Bueno H, Broekhuizen L, Carerj S, Cosyns B, De Backer J, De Bonis M , Dimopoulos K, Drexel H, Flachskampf FA, Hall R, Halvorsen S, Hoen B, Kirchhof P, Lainscak M, Leite-Moreira AF, Lip GY, Mestres CA, Piepoli MF, Punjabi Pp, Rapezzi C, Rosenhek R, Walker DM. Eur Heart J. 2015 Nov 21; 36 (44): 3075-128. He is currently a member of the Task Forces of the following European guidelines: - Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardiac Thoracic Surgery (EACTS) "(version 2017); - Guidelines on Cardiovascular Diseases during Pregnancy; - ESC Focused update on dual anti-platelet therapy. Position Papers of the European Society of Cardiology He also promoted and finalized the following important Position Paper on surgical and trans-catheterization of mitral deficiency by coordinating the activities of two European Society of Cardiology Working Groups (Cardiovascular Surgery and Valvular Heart Disease). This scientific contribution was considered worthy of publication on the prestigious European Heart Journal magazine: - Surgical and interventional management of mitral valve regurgitation: a position statement from the European Society of Cardiology Working Groups on Cardiovascular Surgery and Valvular Heart Disease. De Bonis M , Al-Attar N, Antunes M, Borger M, Casselman F, Falk V, Folliguet T, Iung B, Lancellotti P, Lentini S, Maisano F, Messika-Zeitoun D, ​​Muneretto C, Pibarot P, Pierard L, Punjabi P, Rosenhek R, Suwalski P, Vahanian A, Wendler O, Prendergast B. Eur Heart J. 2016 Jan 7; 37 (2): 133-9 Below is a list of the positions held in the aforementioned companies and scientific associations : - Fellow of the American Heart Association (FAHA) - Member of the SCIENTIFIC & CLINICAL EDUCATION LIFELONG LEARNING (SCILL) COMMITTEE, (already the COUNCIL PROGRAM COMMITTEE) of the American Heart Association Council on Cardiovascular Surgery & Anesthesia (CVSA) for: 1) adult education, 2) program evaluation. - "European Liaison" of the Leadership Committee of the Council on Cardiovascular Surgery and Anesthesia of the American Heart Association - Fellow of the European Society of Cardiology (FESC) - Chairman of the European Society of Cardiology Working Group for Cardiovascular Surgery (2014-2016) - Past-Chairman of the Working Group for Cardiovascular Surgery of the European Society of Cardiology (2016-2018) - Member of the Oversight Committee of the European Society of Cardiology for the Educational Program "Awareness in Mitral Regurgitation" - Member of the European Task Force for Cardiac Surgical Diagnosis Guidelines of the European Society of Cardiology and European Association for Cardiothoracic Surgery (2012 Version) - Member of the European Task Force for Cardiac Surgical Diagnosis Guidelines of the European Society of Cardiology and European Association for Cardiothoracic Surgery (Version 2017) - Member of the European Task Force for Guidelines on Pregnancy Cardiovascular Diseases - Member of the Acquired Cardiac Disease Domain of the European Association for Cardiothoracic Surgery (2012-2016) - Member of the European Association for Cardiothoracic Surgery (EACTS) Academy for Mitral Valve Repairs Surgery Task Force (2016 at the current date) - Secretary of Nucleus of the European Society of Cardiology Working Group for Cardiovascular Surgery (2010-2014) - Member of the Nucleus of the European Society of Cardiology Working Group for Cardiovascular Surgery - Co-Director of the Committee for "Guidelines and Position Papers" and member of the "Commission for Relations with the European Association for Cardiothoracic Surgery" of the Italian Society for Cardiovascular Surgery (2014-2016) Membership in International Societies of Cardiology and Cardiac Surgery Member of the "European Association for Cardiothoracic Surgery" Member of "American Heart Association" Member of the "European Society of Cardiology" Member of the "Italian Society of Cardiac Surgery" EDUCATION AND TRAINING Classic Maturity (60/60) Fifth Class O. Flacco, Power, Italy Degree in Medicine and Surgery (110/110 and Praise), Faculty of Medicine and Surgery, Catholic University of the Sacred Heart of Rome (1993). United States Medical Licensing Examination (USMLE) Certification (1998). Registration at the Order of Doctors of the United Kingdom (United Kingdom) "Full registration" at the General Medical Council under the Medical Act 1983 in the Principal List of the Register of Medical Practitioners (Registration No .: 4486077). Full time fellowship at the European Homograft Bank International Association, Brussels, Belgium (1995-1996). Postgraduate Visiting Fellowships at the Department of Cardiovascular and Thoracic Surgery, Onze Lieve Vrouw Clinic, Aalst, Belgium and the Department of Cardiovascular Surgery, Brugmann University Hospital and Queen Fabiola University Hospital for Children, Brussels, Belgium (1995-1996) Postgraduate Visiting Fellowship, Department of Cardiothoracic Surgery, St. George's Hospital, University of London, London, United Kingdom (1997) Specialist Registrar in Cardiothoracic Surgery, Department of Cardiothoracic Surgery, St. George's Hospital, University of London, London, United Kingdom (1998-1999). Specialization in Cardiac Surgery (50/50 and Praise), Faculty of Medicine and Surgery Catholic University of the Sacred Heart of Rome (1994-1999). Tesi: "Tacrolimus as a rescue immuno-suppressant for refractory rejection after cardiac transplantation" Visiting Fellowship on Circular Mechanical Support Systems (ECMO, VAD, Total Artificial Heart), German Heart Institute, Berlin, Germany (April-May 2008). Prizes and awards for scientific activity Honorable mention during the sixth edition of the "Prize Medicine Prof. P. Petrone" for the degree thesis entitled "Non Pharmacological Treatment of Atrial Fibrillation". Power, December 2, 1995. National Ciociary Medicine Award 2005. Fiuggi, January 22, 2005. DIDACTIC QUALIFICATION Ample academic activity with constant and multi-year didactic experience in cardiac surgery in the Degree courses in Medicine and Surgery, in the Degree Course in Nursing Sciences and in the School of Specialization in Cardiac Surgery of the San Raffaele Health and Welfare University of Milan. As a contract professor, he did the following teaching activity since 2007: - Professor in the disciplinary disciplinary field MED / 23 - Cardiac Surgery under the Specialized Degree Course in Medicine and Surgery. - Professor of Medical discipline MED / 23 - Cardiac Surgery of the Degree Course in Nursing, under the Integrated Course under the title C.14 Clinical Nursing in Specialist Surgery from 2007 to the present date. - Contracted professor at the School of Specialization in Cardiac Surgery from 2007 to the present date. Multi-year tutoring activities of specialists in the field of Cardio-Surgery, Faculty of Medicine and Surgery, San Raffaele University of Milan, Milan. As a contract professor, he held lectures and elective theoretical-practical courses by promoting the student's overall training in the field of cardiovascular discipline. The students' systematically completed questionnaires have confirmed over the years the attitude of teaching and teaching with an interactive and engaging approach. He co-ordinated over 20 graduate theses in Medicine and Surgery or Nursing Sciences as rapporteur or correlator. Teaching activities at the European School for Cardiothoracic Surgery / EACTS Academy In addition to the San Raffaele Life and Health University, he has been teaching intensive teaching and teaching activities since 2003 at the European School for Cardiothoracic Surgery in Bergamo (Italy) and at the Academy of the European Association for Cardiothoracic Surgery in Windsor (Great Britain) (fundamental and advanced courses). In this academy he promoted and developed "Wet-labs" on mitral and tricuspidic repair and replacement surgery. SCIENTIFIC QUALIFICATION High scientific expertise in the field of adult heart surgery with specific reference to the surgical and percutaneous techniques of mitral valve and tricuspid valve, both functional and degenerative . Significant scientific production with continuity characteristics on the aforementioned topics and intense congressional activity especially in the international arena. The specific theme of mitral valve repair surgery was Co-editor of the following book: - Edge-to-Edge Mitral Repair: From a Surgical to a Percutaneous Approach. Alfieri, M. De Bonis , G. La Canna. (editors). Springer International Publishing Switzerland 2015. ISBN: 978-3-319-19892-7 (Print) 978-3-319-19893-4 (Online) DOI 10.1007 / 978-3-319-19893-4_7 and author of 14 chapters in text books or monographs in Cardiology (see list in the list of publications) National research projects, eligible for funding on the basis of competitive calls for peer review. - CCM (National Center for Disease Prevention and Control) Project: Extracorporeal cardiorespiratory support with ECMO (extracorporeal membrane oxygenation) in heart failure patients: improvement of outcomes and prevention of complications "(2008). Partner: CNR Institute of Bioimmagini and Molecular Physiology, Milan Financing: 500,000 euros Role: Operational Manager - Bioactive surface optimization for LVADs (Left Ventricular Assis Devices): BIOSUOVAD (bioactive surfaces for optimized LVAD). Project funded under the call for proposals for experimentation of development initiatives, enhancement of human capital and transfer of research results with direct relocation in the Lombard territory issued by INSTM on 5/12/2012 in implementation of the agreement of collaboration signed between the Lombardy Region and the National Inter-University Consortium for Materials Science and Technology (INSTM) on 13 November 2012. Duration: 15/5 / 2013-15 / 5/2015 Total funding: € 40,000 Role: Co-Reference of the INSTM Research Unit of San Raffaele Hospital Member of the CEC Committee of the Randomized Trial on Tablets and Surgery in Patients with Intermediate Aortic Stenosis (Surtavi Trial) (2014 at the present date) Chairman of the "Adverse Events Safety Board" Prevent Study on Percutaneous Treatment of Tricuspidic Infection with Tri-cinch (4-Tech) System (2013 at the Current Date) Participation in editorial committees of journals International Journal of Cardiology (Associate Editor) Heart, Lung and Vessels (already HSR Proceedings in Intensive Care and Cardiovascular Medicine until 2010). Interactive journal of cardiovascular and thoracic surgery Annals of Cardiology and Cardiovascular Diseases Auditor for the following scientific journals: American Journal of Cardiology Annals of thoracic surgery British Medical Journal on line Circulation European heart journal Expert reviews in cardiology European Journal of Cardiovascular Surgery European Medical Journal Heart Heart, vessels and Lungs Interactive Journal of Thoracic and Cardiovascular Surgery Internationational Journal of Cardiology Journal of thoracic and cardiovascular surgery Journal of cardiovascular disease Nature reviews in cardiology The Lancet

Research Interest

Medicine and Surgery