Dr. Jeremy Squire

Biography

 From 1999-2008  Dr. Jeremy Squire held the positions of Professor in the Department of Laboratory Medicine and Pathobiology at the University of Toronto; a Senior Scientist, Ontario Cancer Institute, and was the first holder of the J.C. Boileau Grant Chair in Oncologic Pathology. In 2008 Dr. Squire moved his laboratory to Kingston, Ontario and accepted the positions of Professor and Research Chair in Molecular Pathology in the Department of Pathology and Molecular Medicine at Queen's University and Kingston General Hospital; and, Director of Translational Laboratory Research, NCIC – Clinical Trials Group.  He also served as Acting Director of the Clinical Cytogenetics Service Laboratory at the Kingston General Hospital from 2009 - 2011. Dr. Squire’s program is strongly oriented towards translational research using molecular, genomic and cytogenetic methods to provide new information and hypotheses concerning the onset, cause and progression of cancer.  He has been a champion of molecular cytogenetic cancer research and was among the first in the world to apply spectral karyotyping (SKY), comparative genomic hybridization (CGH), microarray comparative genomic hybridization, and molecular analysis of epigenomic changes in tumours.  His research groups in Toronto and in Kingston have been among the most productive in this field, with over 300 original peer-reviewed papers, chapters and reviews in the area of the molecular cytogenetics and the genomics of solid tumors and leukemias. With a strong reputation in the use of novel sophisticated technologies for the detection of cancer, he has elucidated clinically important processes that are operative during early steps of cancer initiation, and on multiple changes that affect genes, chromosomes and proteins during tumour progression.

Research Interest

 From 1999-2008  Dr. Jeremy Squire held the positions of Professor in the Department of Laboratory Medicine and Pathobiology at the University of Toronto; a Senior Scientist, Ontario Cancer Institute, and was the first holder of the J.C. Boileau Grant Chair in Oncologic Pathology. In 2008 Dr. Squire moved his laboratory to Kingston, Ontario and accepted the positions of Professor and Research Chair in Molecular Pathology in the Department of Pathology and Molecular Medicine at Queen's University and Kingston General Hospital; and, Director of Translational Laboratory Research, NCIC – Clinical Trials Group.  He also served as Acting Director of the Clinical Cytogenetics Service Laboratory at the Kingston General Hospital from 2009 - 2011. Dr. Squire’s program is strongly oriented towards translational research using molecular, genomic and cytogenetic methods to provide new information and hypotheses concerning the onset, cause and progression of cancer.  He has been a champion of molecular cytogenetic cancer research and was among the first in the world to apply spectral karyotyping (SKY), comparative genomic hybridization (CGH), microarray comparative genomic hybridization, and molecular analysis of epigenomic changes in tumours.  His research groups in Toronto and in Kingston have been among the most productive in this field, with over 300 original peer-reviewed papers, chapters and reviews in the area of the molecular cytogenetics and the genomics of solid tumors and leukemias. With a strong reputation in the use of novel sophisticated technologies for the detection of cancer, he has elucidated clinically important processes that are operative during early steps of cancer initiation, and on multiple changes that affect genes, chromosomes and proteins during tumour progression.