Raj K. Singh Badhan
Resercher
pharma
Farmacore Biotechnology
Japan
Biography
Quantification of central nervous system (CNS) drug levels in brain interstitial fluid (ISF) and cerebrospinal fluid (CSF) is often achieved by complex in vivo experimental procedures, such as microdialysis. This technique has the inherent advantage of directly measuring the concentration of unbound drug in the accessible brain biophase under
Research Interest
physiologically-based pharmacokinetic model, blood–brain barrier, cerebrospinal fluid, unbound fraction, brain