David Lane

Biography

 Professor Sir David Lane obtained his Ph.D. from University College London where he studied auto-immunity. He then did his postdoctoral studies at the Imperial Cancer Research Fund (ICRF) London where he discovered the p53 tumour suppressor protein, and at Cold Spring Harbour Laboratories in New York where he developed monoclonal antibodies and discovered the p68 RNA helicase. In 1980, he returned to UK to set up his own laboratory at Imperial College London before moving his team to the ICRF at Clare Hall in 1985 and subsequently to Dundee University in 1990.  In 1996, he established Cyclacel, a cancer therapeutics company which has developed two new anti-cancer drugs currently in clinical trial. Sir David has won many international prizes and awards for his work and served on the advisory boards of several institutes.  Professor Sir David Lane helped to raise the scientific profile of IMCB by recruiting international leaders in research like Neal Copeland and Nancy Jenkins, Philip Ingham and Jean Paul Thiery. At the same time, he was instrumental in setting up the Experimental Therapeutics Centre (ETC) as a centre of excellence to advance and accelerate drug development in Singapore.

Research Interest

 Cancer