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Hajime Hosoi


Department of Pediatrics
Kyoto Prefectural University of Medicine
Japan

Biography

Dr. Hajime Hosoi has received his PhD in Kyoto Prefectural University of medicine. Currently, he is working as professor in Kyoto Prefectural University of medicine. His research has included Functional biochemistry, Drug development chemistry, Pediatrics Based on this research and fellowship training he has received several awards and honors. He has authored several research articles.

Research Interest

Functional biochemistry, Drug development chemistry, Pediatrics

Publications

  • Kawashima-Goto S, Imamura T, Tomoyasu C, Yano M, Yoshida H, Fujiki A, Tamura S, Osone S, Ishida H, Morimoto A, Kuroda H, Hosoi H. BCL2 Inhibitor (ABT-737): A restorer of prednisolone sensitivity in early T-cell precursor-acute lymphoblastic leukemia with high MEF2C expression? PLoS One. 2015 Jul 14.

  • Yoshida H, Miyachi M, Sakamoto K, Ouchi K, Yagyu S, Kikuchi K, Kuwahara Y, Tsuchiya K, Imamura T, Iehara T, Kakazu N, Hojo H, Hosoi H. PAX3-NCOA2 fusion gene has a dual role in promoting the proliferation and inhibiting the myogenic differentiation of rhabdomyosarcoma cells. Oncogene. 2014; 33: 5601-8.

  • Yoshida M, Kitaoka S, Egawa N, Yamane M, Ikeda R, Tsukita K, Amano N, Watanabe A, Morimoto M, Takahashi J, Hosoi H, Nakahata T, Inoue H, Saito MK. Modeling the early phenotype at the neuromuscular junction of spinal muscular atrophy using patient-derived iPSCs. Stem Cell Reports. 2015; 4: 561-8.

  • Yamashita S, Chiyonobu T, Yoshida M, Maeda H, Zuiki M, Kidowaki S, Isoda K, Morimoto M, Kato M, Saitsu H, Matsumoto N, Nakahata T, Saito MK, Hosoi H. Mislocalization of syntaxin-1 and impaired neurite growth observed in a human iPSC model for STXBP1-related epileptic encephalopathy. Epilepsia. 2016; 57:e81-6.

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