Yukihiro Itoh
Assistant professor
Department of Chemistry
Kyoto Prefectural University of Medicine
Japan
Biography
Dr. Yukihiro ITOH has received his PhD in The University of Tokyo in 2011. Currently, he is working as Assistant Professor in Kyoto Perfectural University. His research has included development of therapeutic agents, medicinal chemistry and chemical biology. Based on this research and fellowship training he/she has received several awards and honors, such as Research Fellow for Young Scientists, Japan Society for the Promotion of Science, April 2010, The Uehara Memorial Foundation Abroad Research Fellowships December 2011 (Being excused by employment of Kyoto Prefectural University of Medicine). He has authored research articles.
Research Interest
development of therapeutic agents, medicinal chemistry and chemical biology
Publications
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Yukihiro I, Miki S, Taiji M, Yusuke O, Zi H, Kazunori T, Takayoshi S. False HDAC inhibition by aurone compound. Chemical & Pharmaceutical Bulletin (2016) 64: 1124-1128.
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Shin M, Misaho A, Yosuke O, Yukihiro I, Shusuke Y, Mitsuharu M, Tomoyuki T, Yoshihiro S, Toshiyuki S, Takayoshi S, Kenichiro I, Junichiro Y. C-H Activation Enables Rapid Structure-Activity Relationship Study of Arylcylclopropyl Amines for Potent and Selective LSD1 Inhibitors. Organic & Biomolecular Chemistry (2016) 14: 8576-8585.
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Yosuke O, Yukihiro I, Asako K, Kiminori O, Yasuyuki E, Mitsuharu M, Yoshihiro S, Toshiyuki S, Takayoshi S. Targeting Cancer with PCPA-Drug Conjugates: LSD1 Inhibition-Triggered Release of 4-Hydroxytamoxifen. Angewandte Chemie International Edition (2016) 55: 16115-16118.
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Keiichiro O, Takuji S, Risa O, Nobumichi O, Takayuki H, Norihito S, Yosuke D, Ryo S, Asato I, Haruka K, Yukihiro I, Minoru I, Yuichi H, Masaaki K, Hiroyuki S, Mikihiko N. Targeted degradation of proteins localized in subcellular compartments by hybrid small molecules. Molecular pharmacology (2017) 91: 159-166.