Sumitani Jun-ichi
Applied life sciences
professor
Osaka Prefecture University
Japan
Biography
I’m studying on microbial enzymes for industrial application. My works will cover isolation of useful microbes from soil, and purification, characterization, and functional optimization of their enzymes through the techniques for protein and gene manipulation. Present works focus on as follows.Analysis of interaction between alpha-amylases and proteinaceous inhibitors, and development of inhibitors to quantify serum amylase isozymes for diagnosis of pancreatic diseases.Functional analysis of starch-binding domain (SBD) and development for an amylase with high activity toward raw starches using SBD. Improvement of some properties (stability, specificity, etc…) of diagnostic enzymes for industrial application.
Research Interest
Biomass , glucosidase inhibitors
Publications
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Nakazawa H, Kawai T, Ida N, Shida Y, Kobayashi Y, Okada H, Tani S, Sumitani JI, Kawaguchi T, Morikawa Y, Ogasawara W. Construction of a recombinant Trichoderma reesei strain expressing Aspergillus aculeatus βâ€glucosidase 1 for efficient biomass conversion. Biotechnology and bioengineering. 2012 Jan 1;109(1):92-9.
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SUMITANI JI, TOTTORI T, KAWAGUCHI T, Motoo AR. New type of starch-binding domain: the direct repeat motif in the C-terminal region of Bacillus sp. no. 195 α-amylase contributes to starch binding and raw starch degrading. Biochemical Journal. 2000 Sep 1;350(2):477-84.
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Kawaguchi T, Enoki T, Tsurumaki S, Sumitani JI, Ueda M, Ooi T, Arai M. Cloning and sequencing of the cDNA encoding β-glucosidase 1 from Aspergillus aculeatus. Gene. 1996 Sep 16;173(2):287-8.
