Erik Arner
Unit Leader
Molecular Network Control Genomics Unit
The Institute of Physical and Chemical Research (RIKEN)
Japan
Biography
Based on omics technologies developed at DGT, in particular unique transcriptome technology such as CAGE, we develop systems for identifcation of target proteins suitable for regulatory molecules and exploration of the effect of regulatory molecules. Specifically, we aim to develop technology for 1) identification of the best path to control a target signal transduction pathway, 2) exploration of the transcriptional effect of regulatory molecules at the cellular level, and 3) analysis of targets and regulatory molecules at the single cell level.
Research Interest
Molecular Biology & Genetics
Publications
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Forrest ARR, Kawaji H, Rehli M, Baillie JK, de Hoon MJL, Haberle V, Lassmann T, Kulakovskiy IV, Lizio M, Itoh M, Andersson R, Mungall CJ, Meehan TF, Schmeier S, Bertin N, Jørgensen M, Dimont E, Arner E et al.: "A promoter level mammalian expression atlas." Nature. 2014; 507(7493):462-70.
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Andersson R, Gebhard C, Miguel-Escalada I, Hoof I, Bornholdt J, Boyd M, Chen Y, Zhao X, Schmidl C, Suzuki T, Ntini E, Arner E et al.: "An atlas of active enhancers across human cell types and tissues." Nature. 2014; 507(7493):455-61.
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Arner E, Daub CO, Vitting-Seerup K, Andersson R et al.: "Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells." Science. 2015; 347(6225):1010-4.
