Natsuko Chiba
Professor
Department of c
Tohoku University
Japan
Biography
Dr. Natsuko Chiba, is a Professor of Clinical Oncology, at Tohoku University School of medicine. She is M.D. and Ph.D. Her research themes are Regulatory mechanism of breast cancer-related molecules in mitosis, Response of tumor suppressor molecules to DNA damage. Research Keywords for her are tumor suppressor gene, mitosis, DNA damage response, hereditary cancer, centrosome regulation.
Research Interest
cell biology, molecular biology, animal experiment
Publications
-
Chiba, N., Suldan, Z., Freedman, L. P., & Parvin, J. D. (2000). Binding of liganded vitamin D receptor to the vitamin D receptor interacting protein coactivator complex induces interaction with RNA polymerase II holoenzyme. Journal of Biological Chemistry, 275(15), 10719-10722.
-
Ransburgh, D. J., Chiba, N., Ishioka, C., Toland, A. E., & Parvin, J. D. (2010). Identification of breast tumor mutations in BRCA1 that abolish its function in homologous DNA recombination. Cancer research, 70(3), 988-995.
-
Chiba, N., & Parvin, J. D. (2002). The BRCA1 and BARD1 association with the RNA polymerase II holoenzyme. Cancer research, 62(15), 4222-4228.
-
Mukouyama, Y. S., Chiba, N., Hara, T., Okada, H., Ito, Y., Kanamaru, R., ... & Watanabe, T. (2000). The AML1 transcription factor functions to develop and maintain hematogenic precursor cells in the embryonic aorta–gonad–mesonephros region. Developmental biology, 220(1), 27-36.
-
Mukouyama, Y. S., Chiba, N., Hara, T., Okada, H., Ito, Y., Kanamaru, R., ... & Watanabe, T. (2000). The AML1 transcription factor functions to develop and maintain hematogenic precursor cells in the embryonic aorta–gonad–mesonephros region. Developmental biology, 220(1), 27-36.
-
Okada, H., Watanabe, T., Niki, M., Takano, H., Chiba, N., Yanai, N., ... & Ito, Y. (1998). AML1 (-/-) embryos do not express certain hematopoiesis-related gene transcripts including those of the PU. 1 gene. Oncogene, 17(18), 2287-2293.
-
Starita, L. M., Horwitz, A. A., Keogh, M. C., Ishioka, C., Parvin, J. D., & Chiba, N. (2005). BRCA1/BARD1 Ubiquitinate Phosphorylated RNA Polymerase II. Journal of Biological Chemistry, 280(26), 24498-24505.
