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Takaaki Abe

Professor
Department of Clinical Biology and Hormonal Regulation
Tohoku University
Japan

Biography

Dr. Takaaki Abe, is a Professor of Clinical Biology and Hormonal Regulation, at Tohoku University School of medicine. He is M.D. and Ph.D. His research themes are Mitochondrial Medicine, CKD and gut micorbiota, Transporter Medicine. Research Keywords for him are transporter, gut microbiota, tRNA, mitochondrial diseases, anti-fibrosis.

Research Interest

transporter, mitochondria, flux analyzser, tRNA, 1-methyladenosine

Publications

  • Sasaki, M., Suzuki, H., Ito, K., Abe, T., & Sugiyama, Y. (2002). Transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II cell monolayer expressing both human organic anion-transporting polypeptide (OATP2/SLC21A6) and multidrug resistance-associated protein 2 (MRP2/ABCC2). Journal of Biological Chemistry, 277(8), 6497-6503.

  • Abe, T., Unno, M., Onogawa, T., Tokui, T., Kondo, T. N., Nakagomi, R., ... & Nunoki, K. (2001). LST-2, a human liver-specific organic anion transporter, determines methotrexate sensitivity in gastrointestinal cancers. Gastroenterology, 120(7), 1689-1699.

  • Abe, T., Kakyo, M., Sakagami, H., Tokui, T., Nishio, T., Tanemoto, M., ... & Yawo, H. (1998). Molecular characterization and tissue distribution of a new organic anion transporter subtype (oatp3) that transports thyroid hormones and taurocholate and comparison with oatp2. Journal of Biological Chemistry, 273(35), 22395-22401.

  • Abe, T., Kakyo, M., Tokui, T., Nakagomi, R., Nishio, T., Nakai, D., ... & Matsuno, S. (1999). Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1. Journal of Biological Chemistry, 274(24), 17159-17163.

  • Abe, T., Sugihara, H., Nawa, H., Shigemoto, R., Mizuno, N., & Nakanishi, S. (1992). Molecular characterization of a novel metabotropic glutamate receptor mGluR5 coupled to inositol phosphate/Ca2+ signal transduction. Journal of Biological Chemistry, 267(19), 13361-13368.

  • Shigemoto, R., Kinoshita, A., Wada, E., Nomura, S., Ohishi, H., Takada, M., ... & Mizuno, N. (1997). Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus. Journal of Neuroscience, 17(19), 7503-7522.

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