Takahiro Arima
Professor
Department of Informative Genetics
Tohoku University
Japan
Biography
Dr. Takahiro Arima, is a Professor of Medical Genetics, at Tohoku University School of medicine. He is M.D. and Ph.D. His research themes are Genomic imprinting and mammalion evolution, Molecular mechanism of genomic imprinting phenomenon, Study on association between human assisted reproductive technology (ART) and congenital imprinting diseases. Research Keywords for him are Genomic imprinting, Epigenetics, Placenta, Assisted reproductive technology (ART), Evolution.
Research Interest
DNA methylation, Histone modification , RNA sequence
Publications
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Arima, T., Kamikihara, T., Hayashida, T., Kato, K., Inoue, T., Shirayoshi, Y., ... & Wake, N. (2005). ZAC, LIT1 (KCNQ1OT1) and p57 KIP2 (CDKN1C) are in an imprinted gene network that may play a role in Beckwith–Wiedemann syndrome. Nucleic acids research, 33(8), 2650-2660.
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Kobayashi, H., Hiura, H., John, R. M., Sato, A., Otsu, E., Kobayashi, N., ... & Yaegashi, N. (2009). DNA methylation errors at imprinted loci after assist
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Kamiya, M., Judson, H., Okazaki, Y., Kusakabe, M., Muramatsu, M., Takada, S., ... & Satomura, K. (2000). The cell cycle control gene ZAC/PLAGL1 is imprinted—a strong candidate gene for transient neonatal diabetes. Human molecular genetics, 9(3), 453-460.
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Kato, K., Yoshimoto, M., Kato, K., Adachi, S., Yamayoshi, A., Arima, T., ... & Wake, N. (2007). Characterization of side-population cells in human normal endometrium. Human Reproduction, 22(5), 1214-1223.
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Watanabe, T., Tomizawa, S. I., Mitsuya, K., Totoki, Y., Yamamoto, Y., Kuramochi-Miyagawa, S., ... & Gotoh, K. (2011). Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus. Science, 332(6031), 848-852.
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Kobayashi, H., Sato, A., Otsu, E., Hiura, H., Tomatsu, C., Utsunomiya, T., ... & Arima, T. (2007). Aberrant DNA methylation of imprinted loci in sperm from oligospermic patients. Human molecular genetics, 16(21), 2542-2551.
