Akira Otaka
Professor
Faculty of Pharmaceutical Sciences
University of Tokushima
Japan
Biography
Akira Otaka has done his PhD from Kyoto University in 1989. Currently he is working as Professor in Faculty of Pharmaceutical Science at Tokushima University. His research interests are Biological organic chemistry, organic synthetic chemistry, peptide / protein chemistry, chemical biology, Pioneering efficient protein chemistry synthesis method for establishment of drug discovery base. Several Papers of his work were published in reputed international journals. He is also the member of The Pharmaceutical Society of Japan, Japan Peptide Society.
Research Interest
Biological organic chemistry, organic synthetic chemistry, peptide / protein chemistry, chemical biology.
Publications
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Keisuke Aihara, Tsubasa Inokuma, Takahisa Jichu, Zhenjian Lin, Feixue Fu, Kosuke Yamaoka, Akira Shigenaga, David A. Hutchins, Eric W. Schmidt and Akira Otaka. Cysteine-free intramolecular ligaiton of N-sulfanylethylanilide peptide using 4-mercaptobenzylphosphonic acid: Synthesis of cyclic peptide, trichamide. Synlett. 2017, 28(15): 1944-1949.
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Taiki Kohiki, Yusuke Nishikawa, Tsubasa Inokuma, Akira Shigenaga and Akira Otaka. Chemical synthetic platform for chlorpromazine oligomers that were reported as photo-degradation products of chlorpromazine. Chemical & Pharmaceutical Bulletin. 2017.
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Kosuke Tanegashima, Rena Takahashi, Hideko Nuriya, Naoto Naruse, Kohei Tsuji, Akira Shigenaga, Akira Otaka and Takahiko Hara. CXCL14 acts as a specific carrier of CpG into dendritic cells and activates Toll-like receptor 9-mediated adaptive immunity. EBioMedicine. 2017, 24: 247-256.