Choi, Wonshik
Associate Director
Center for Molecular Spectroscopy and Dynamics
Institute for Basic Science
Korea
Biography
Dr. Wonshik Choi received his B.S. (1997) and M.S. (1999) degrees in Physics at Seoul National University and Ph.D. (2004) degree in Physics at the same university under the direction of Prof. Kyungwon An. He then joined Michael S. Feld group at MIT in 2006 as a postdoctoral researcher. In his postdoctoral work, he invented tomographic phase microscopy (TPM), a novel optical microscopy method which enables quantitative 3-D imaging of the refractive index of living cells and tissues (Nature Methods 4, 717 (2007)). Afterwards he joined Korea University in September, 2009 as an assistant professor of the Department of Physics. Since then, he has embarked on researches for overcoming the effect of tissue turbidity with an aim to imaging deep inside biological tissues. His recent works include the overcoming of diffraction limit using a disordered medium (Physical Review Letters 107, 023902 (2011)), the development of a scanner-free endoscopic imaging using a single multimode fiber (Physical Review Letters 109, 203901 (2012)), the demonstration of maximal energy transport through turbid medium (Nature Photonics 6, 581 (2012)), and the development of ultrahigh-resolution and deep-tissue imaging method (Nature Photonics 9, 253 (2015)).
Research Interest
On the ground of recent studies that have advanced the control of wave propagation through disordered media, his laboratory has set the research direction to resolve tissue turbidity for super-depth and high-resolution optical imaging, light manipulation and phototherapy,
Publications
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Kim M, Choi W, Choi Y, Yoon C, Choi W. Transmission matrix of a scattering medium and its applications in biophotonics. Optics Express. 23: 12648-68. PMID 26074520
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Choi W, Kim M, Kim D, Yoon C, Fang-Yen C, Park QH, Choi W. Preferential coupling of an incident wave to reflection eigenchannels of disordered media. Scientific Reports. 5: 11393. PMID 26078088 DOI: 10.1038/srep11393
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Yang TD, Choi W, Yoon TH, Lee KJ, Lee JS, Joo JH, Lee MG, Yim HS, Choi KM, Kim B, Lee JJ, Kim H, Lee DY, Jung KY, Baek SK. In vivo photothermal treatment by the peritumoral injection of macrophages loaded with gold nanoshells. Biomedical Optics Express. 7: 185-93.
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Yoon C, Kang M, Hong JH, Yang TD, Xing J, Yoo H, Choi Y, Choi W. Removal of back-reflection noise at ultrathin imaging probes by the single-core illumination and wide-field detection. Scientific Reports. 7: 6524.