Dinish U.s

Biography

"Dr. Dinish obtained his Ph.D. in bio-optics and imaging in 2005 from Nanyang Technological University (NTU), Singapore. Currently, he is working as Research Scientist at Singapore Bioimaging Consortium, A*STAR and concentrating on the development of optical and multi modal imaging techniques for translational research. His research interests are in translational biophotonics and specifically aim to develop photonics technologies for various applications in biomedicine. Various photonics techniques being researched for biosensing applications include Raman and surface enhanced Raman scattering (SERS). SERS platforms are developed for biomarker sensing for both preclinical and clinical applications using novel substrate and metallic nanoparticle configurations. SERS active nanoparticles (SERS nanotags) are also developed for multiplex detection of biomarkers both ex vivo and in vivo in an animal model. Cutting edge specialty fiber based SERS active optical probes are also being developed by combining novel nanomaterial strategies for direct biomarker sensing in clinical biofluids. Multifunctional fiber optic probe by strategically combining various optical sensing methodologies is also developed to extract complementary information in preclinical and clinical biosensing applications. On the other hand, photoacoustic imaging (PAI, both tomography and microscopy) is studied for various translational bioimaging applications. Multimodal optical contrast agents (in the form of chemical probes) for PAI and SERS are also used for various in vivo bioimaging applications. "

Research Interest

"Biophotonics and Tarnslational medicine Optical instrumentation for bio-diagnostics Multimodality optical imaging for biosensing and imaging "