Liu Chuan Fa
"Division of Physics & Applied Physics School of Physical &
Korea University
Korea
Biography
"ACADEMIC AND PROFESSIONAL EXPERIENCE 2003 – present Associate Professor, School of Biological Sciences, Nanyang Technological University, Singapore 2002 – 2003 Research Scientist IV, Amgen Research, Amgen Inc., USA 2000 – 2002 Research Scientist III, Amgen Research, Amgen Inc., USA 1999 – 2000 Research Scientist II, Amgen Research, Amgen Inc., USA 1996 – 1999 Research Scientist I, Amgen Research, Amgen Inc., USA 1992 – 1996 Research Instructor, Vanderbilt University Medical Centre, USA Postdoctoral Research Associate, Vanderbilt University Medical Centre, USA 1990 – 1992 Postdoctoral Associate, The Rockefeller University, USA 1989 – 1990 Research Associate, CNRS, Centre CNRS-INSERM de Pharmacologie-Endocrinologie, Montpellier, France POSITIONS HELD Current Member, NTU Teaching Council (appointed by the Provost) "
Research Interest
"New strategies for peptide and protein drug development; peptide drug delivery; peptide and protein bioconjugates and antibody-drug conjugates as drug modalities; new peptide leads from phage display and natural sources. Medicinal chemistry and structure-based drug design; peptidomimetics; combinatorial chemistry for drug lead discovery. Development and use of peptide nucleic acid analogs as antisense and antigene agents. Pharmacokinetic (PK) studies using LC-MS."
Publications
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Nguyen GK, Qiu Y, Cao Y, Hemu X, Liu CF, Tam JP. Butelase-mediated cyclization and ligation of peptides and proteins. Nature protocols. 2016 Oct 1;11(10):1977-88.
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Pasunooti KK, Yang R, Banerjee B, Yap T, Liu CF. 5-Methylisoxazole-3-carboxamide-Directed Palladium-Catalyzed γ-C (sp3)–H Acetoxylation and Application to the Synthesis of γ-Mercapto Amino Acids for Native Chemical Ligation. Organic letters. 2016 May 24;18(11):2696-9.
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Nguyen GK, Qiu Y, Cao Y, Hemu X, Liu CF, Tam JP. Butelase-mediated cyclization and ligation of peptides and proteins. Nature protocols. 2016 Oct 1;11(10):1977-88.
