Young Chan Chae
Assistant Professor
school of life sciences
Ulsan National Institute of Science and Technology
Korea
Biography
2017 - Present: Assistant Professor, UNIST 2013 - 2017: Associate Staff Scientist, Wistar Institute Cancer Center, USA 2010 - 2013: Postdoctoral Fellow, Wistar Institute Cancer Center, USA 2006 - 2010: Senior Researcher, POSTECH Biotech Center 2001 - 2006: Ph.D., Life Science, POSTECH 1997 - 2001: B.S., Life Science, POSTECH
Research Interest
Metabolic adaptation and autophagy in cell survival, cancer progression and metastasis, Mechanism of tumor therapeutic resistance and Development of cancer therapeutics.
Publications
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Caino MC, Chae YC, Vaira V, Ferrero S, Nosotti M,et al.(2013)Metabolic Stress Control of Cytoskeletal Dynamics and Metastasis.Journal of Clinical Investigation.123:2907-2920
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Ghosh JC , Siegelin MD, Vaira V, Faversani A, Chae YC,et al.(2015) Adaptive Mitochondrial Reprogramming and Resistance to PI3K Therapy. Journal of the National Cancer Institute.
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Caino MC, Ghosh JC, Chae YC, Vaira V, Faversani A,et al.(2015)PI3K Therapy Reprograms Mitochondrial Trafficking to Fuel Tumor Cell Invasion. Proc Natl Acad Sci USA 112:8638-8643.
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Chae YC, Vaira V, Caino MC, Tang HY, Seo JH, et al.(2016)Mitochondrial Akt Regulation of Hypoxic Metabolic Reprogramming. Cancer Cell,30:257-272
