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Gunars Duburs

Professor
Chemical and Biological Sciences
Latvian Institute of Organic Synthesis
Latvia

Biography

Dr. Gunars DUBURS is currently working as a Professor in the Department of Chemical and Biological Sciences, Latvian Institute of Organic Synthesis , Latvia. His research interests includes Heterocyclic Chemistry (mainly partially hydrogenated azines: dihydro- (tetrahydro-) pyridines, pyrimidines, polycyclic derivatives) - studies of chemical, physical chemical and biological properties. He  is serving as an editorial member and reviewer of several international reputed journals. Dr. Gunars DUBURS is the member of many international affiliations. He  has successfully completed his Administrative responsibilities. He  has authored of many research articles/books related to Heterocyclic Chemistry (mainly partially hydrogenated azines: dihydro- (tetrahydro-) pyridines, pyrimidines, polycyclic derivatives) - studies of chemical, physical chemical and biological properties.

Research Interest

Heterocyclic Chemistry (mainly partially hydrogenated azines: dihydro- (tetrahydro-) pyridines, pyrimidines, polycyclic derivatives) - studies of chemical, physical chemical and biological properties Medicinal Chemistry (synthesis and studies of neurotropic, cardiovascular, antioxidative, membrane protective, radioprotective, UV-protective, peptidomimetic, gene transfection agents) Research in organic chemistry, especially – partially hydrogenated nitrogen and sulfur containing heterocycles, medicinal and food chemistry (antioxidants), drug research (radioprotectors, cardiovascular compounds and neuroprotectors). Scientific articles – 475, 64 patents, 105 authors certificates. Developed and registered 2 original preparations for medicine: antihypertensive, antianginal preparation foridone (riodipine), radioprotector diethone; for agriculture – antioxidant, feed and food stabilizer diludine; proposed preparations for organic analysis.

Publications

  • Free radicals at electrochemical reduction of 3-nitro-1,4-dihydropyridin derivatives . - Chem. Heterocycl. Comp., 1995, N 3, pp. 355-364

  • The effect of some 1,4-dihydropyridine and 1,4-dihydroindeno[1,2-b]pyridine derivatives on glutathione S-transferase activity in vitro. - Biochem. Pharmacol

  • The mechanisms of the oxidation of NADH analogues. 1. Photochemical oxidation of N-unsubstituted 1,4-dihydropyridines by various acceptors. -

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