Aurelie Poli

Biography

Human CD56dimCD16dim Cells As an Individualized Natural Killer Cell Subset.   Human CD56bright NK Cells: An Update.   Combining NK cells and mAb9.2.27 to combat NG2-dependent and anti-inflammatory signals in glioblastoma   Elevated CD3+ and CD8+ tumor-infiltrating immune cells correlate with prolonged survival in glioblastoma patients despite integrated immunosuppressive mechanisms in the tumor microenvironment and at the systemic level   Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia. Targeting glioblastoma with NK cells and mAb against NG2/CSPG4 prolongs animal survival.   NK cells in central nervous system disorders   Mouse lung and spleen natural killer cells have phenotypic and functional differences, in part influenced by macrophages   Expression of the progenitor marker NG2/CSPG4 predicts poor survival and resistance to ionising radiation in glioblastoma.   Increased Th2 cytokine secretion, eosinophilic airway inflammation, and airway hyperresponsiveness in neurturin-deficient mice.

Research Interest

Research Biotechnology