Daniel Ayoub

Biography

Research scientist in analytical biochemistry, I have a broad experience in mass spectrometry applied to proteomics, protein structural analysis, and structural biochemistry. Throughout my career I acquired and developed the following experience and expertise:  Management skills - Research project management. - Strong problem solving and management of complex situations skills - Effective leadership acquired through managing technicians, engineers and PhD students - Managing and coordinating multidisciplinary projects in collaboration with international  industrial and academic research groups and organizations. - Strong communication skills and good persuasion capabilities. Technical skills - Characterization of monoclonal antibodies (mAbs) and antibody drug conjugates (ADCs), mAbs derivatives and biosimilars. - Proteomics, characterization of protein post-translational modifications. Protein/peptide quantification (PRM/SRM, Label Free, SILE). - Instrumental and methodological development in mass spectrometry and liquid chromatography. - Native mass spectrometry, characterization of noncovalent complexes. - Development of MS-Proteomic methods for biomarker discovery, signaling pathways and drug mechanisms of action studies. - MS-based methods for pharmacokinetic studies of mAbs and ADCs. - Good knowledge and interest in molecular biology and Immunology - Bioinformatics, statistics and result validation

Research Interest

Biochemistry