Luxembourg Institute of Science and Technology
During the last decade the main research interest was related to long-term effects of early life stage exposure to low and thereby environmentally relevant concentrations of a wide range of classes of compounds including but not restricted to environmental contaminants. Most often polychlorinated biphenyls (PCBs), brominated flame-retardants (PBDEs etc.) and their metabolites were chosen as model compounds with additional research on heavy metals, mycotoxins, allergens etc. Toxicity of nanomaterials and nanoparticles has attained a main focus and several projects funded by the FNR, FP7 and H2020 are currently ongoing. The development of highly relevant 3D-in vitro models is the core business of the research group. Furthermore two projects related to Human Biomonitoring have recently been finished.