Medical Sciences

Medical Sciences Experts

Chuxia Deng

Health Sciences
University of Macau


Chuxia DENG received his Bachelor's degree from Department of Biology, West China Normal University, Nanchong, China in 1982 and Master's from Institute of Hydrobiology, Academia Sinica, Wuhan, China (1984).

Research Interest

Oncogenes and tumor suppressor genes, Sirtuins; Cancer, Metabolic diseases; Aging; Stem cells, Cancer metastasis, Drug development, Cell cycle, Bioinformatics, Genome stability, Development, Gene targeting


  • Xiaoling Xu, ZoĆ« Weaver, Steven P. Linke, Cuiling Li, Jessica Gotay, Xin-Wei Wang, Curtis C. Harris, Thomas Ried and Chuxia Deng (1999). Centrosome Amplification and a Defective G2-M Checkpoint Induce Genetic Instability in BRCA1 Exon 11 Isoform-Deficient Cells. Molecular Cell 3, 389-396. PMID: 10198641.

  • Chuxia Deng, Tony Wynshaw-Boris, Fen Chou, Ann Kuo and Philip Leder (1996). FGFR-3 is a negative regulator in bone growth. Cell 84, 911-921. PMID: 8601314.

  • Chuxia Deng, Pumin Zhang, J. Wade Harper, Stephen J. Elledge, and Philip Leder (1995). Mice lacking p21cip1/waf1 undergo normal development, but are defective in G1 checkpoint control. Cell 82, 675-684.

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