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Department of Neuroscience


Porreca-Frank is Professor of Pharmacology and Anesthesiology at the University of Arizona. He has authored more than 500 original, peer-reviewed articles addressing mechanisms related to pain and migraine, and how circuits are engaged to produce pain relief. These studies have explored descending pain modulation and adaptations that occur in chronic pain as well as cortical circuits and the role of endogenous opioids. Current research interests include understanding pain-induced motivational behaviour and reward circuits and their relationship to learning in chronic pain and migraine. Dr. Porreca has been recognized as a "Highly Cited" investigator by Pub Med and one of the 10 most cited pharmacologists in the world by the American Society of Pharmacology and Experimental Therapeutics. For his discoveries on the adaptive nature of the brain following nerve injury, Dr. Porreca was honored by the International Association for the Study of Pain with the Melzack Award, the American Pain Society with the Frederick W. Kerr Award for Basic Research in Pain, as well as by NIH Merit Award and many visiting Professorships.

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