Molecular Biology

Molecular Biology Experts

Diana Cruz-topete

Molecular Endocrinology
Institut Pasteur de Bangui

Diana Cruz-topete


The Flow Cytometry Center provides state of the art instrumentation and resources for fluorescent analysis of cells at the single cell level, including high-speed fluorescence-activated cell sorting. Our goal is to provide expertise in flow cytometry in the areas of experimental design, instrument knowledge and training, data analysis and cell sorting. We support the mission of NIEHS by providing the latest advances in flow cytometric technology to the institute for reducing the burden of diseases and dysfunctions associated with the environment.

Research Interest

Major areas of research: Glucocorticoid receptors and their actions on the inflammatory response Regulation of apoptosis in normal and neoplastic cells Animal models for studying glucocorticoid actions


  • Cloning novel inhibitors of apoptosis The role of cell volume regulation and ion channels in apoptosis Defining how glucocorticoid activate and inhibit apoptosis in cancer cells

  • Current projects: Mutual interference of signaling between the glucocorticoid receptor and NF-κB The role of glucocorticoid receptor phosphorylation in signal transduction The transcriptional and translational regulation of glucocorticoid receptor gene expression

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