Bioinformatics & Systems Biology

Bioinformatics & Systems Biology Experts

Joan P. Packenham

Institut Pasteur de Bangui


The overall mission of the Office of Human Research Compliance (OHRC) is to manage a comprehensive Human Research Protection Program at the National Institute of Environmental Health Sciences (NIEHS). The OHRC accomplishes its mission by providing professional advice and leadership to NIEHS in the protection of human subjects participating in research through: Maintaining compliance by providing clarification and guidance in interpreting the Federal Regulations for the protection of human subjects, 45CFR46 and 21CFR50 & 56; NIH and NIEHS policies and guidance; and state regulations and guidance. Providing guidance to PIs during protocol development.

Research Interest



  • Current projects: Environmental Risk Factors for the Anti-Synthetase Syndrome - An ongoing study enrolling patients who have been diagnosed with polymyositis or dermatomyositis in the past year. The purpose of this study is to attempt to determine what environmental risk factors may lead to the development of idiopathic inflammatory myopathy (IIM) overall and in particular what risk factors lead someone to develop one type of IIM over another. Pathogenic Studies in Families with Twins or Siblings Discordant for System

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