Cellular & Molecular Pathology
Institut Pasteur de Bangui
Mark Cesta, D.V.M., Ph.D., D.A.C.V.P., is a staff scientist and board certified pathologist working with David Malarkey, Ph.D., in the NTP Pathology Group. His current research focuses on growth factors involved in the pulmonary fibrotic effects of single- and multi-walled carbon nanotubes in rats and the contribution of pre-exposure to bacterial endotoxin. This work is being conducted in collaboration with scientists at North Carolina State University and The Hamner Institutes for Health Sciences in Research Triangle Park, North Carolina. Other projects include pathology oversight and preparation of the technical report for the NTP studies of b-myrcene, 1-bromopropane, methyl trans-styryl ketone, Cimstar 3800 and Trim SC210 (metal working fluids), and trimethylolpropane triacrylate, collaboration on the Wistar Han rat background lesion atlas and an atlas of reproductive lesions in rodents, and immunohistochemical characterization of urinary bladder tumors in rats exposed to o-nitroanisole.
Toxicologic pathology, especially of the respiratory and cardiopulmonary systems Pulmonary fibrosis Animal models of pulmonary fibrosis Growth factors involved in pulmonary fibrosis Pathology of genetically-engineered laboratory animals
Cesta MF, Malarkey DE, Herbert RA, Brix A, Hamlin MH 2nd, Singletary E, Sills RC, Bucher JR, Birnbaum LS. The National Toxicology Program Web-based nonneoplastic lesion atlas: a global toxicology and pathology resource. Toxicologic pathology 2014 42(2):458-460.
Surh I , Rao DB, Cesta MF, Hébert CD, Mann JF, Cunny H, Kissling GE, Malarkey D, Chhabra RS. Species and gender differences in the carcinogenic activity of trimethylolpropane triacrylate in rats and mice. Food and chemical toxicology 2014 66:254-261.