Institut Pasteur de Bangui
Yucel Akgul received an MD from the Cumhuriyet University School of Medicine in 1998 and a PhD in Physiology from the West Virginia University in 2007. He was a postdoctoral fellow from 2008-2014 with Dr. Mala Mahendroo at the UT Southwestern Medical Center. He joined the faculty at UT Southwestern in 2016. The goal of his lab is to understand molecular mechanism of extracellular matrix (ECM) remodeling in wound healing to develop therapies and diagnostic tools against delayed and abnormal wound healing. Delayed and abnormal wound healing is a serious health problem for millions of patients suffering each year from non- healing skin ulcers, or from excessive scarring after trauma.
Extracellular matrix (ECM) remodeling in wound healing
The methoxychlor metabolite, HPTE, inhibits rat luteal cell progesterone production. Akgul Y, Derk RC, Meighan T, Rao KM, Murono EP Reprod. Toxicol. 2011 Jul 32 1 77-84
Antioxidant protects against increases in low molecular weight hyaluronan and inflammation in asphyxiated newborn pigs resuscitated with 100% oxygen. Østerholt HC, Dannevig I, Wyckoff MH, Liao J, Akgul Y, Ramgopal M, Mija DS, Cheong N, Longoria C, Mahendroo M, Nakstad B, Saugstad OD, Savani RC PLoS ONE 2012 7 6 e38839