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José Federico Del Río Portilla

Researcher
Department of Biomacromolecules
National Autonomous University of Mexico
Mexico

Biography

Dr. José Federico Del Río Portilla is working as a Researcher in the Department of Biomacromolecules in National Autonomous University of Mexico, Mexico. he has completed his Postdoctoral position: Harvard Medical School, from 1996-1998. Structural elucidation of proteins by NMR, Ph.D. Physical Chemistry, National Autonomous University of Mexico, 1995. Visiting scholar. Two years at Cambridge University, England, 1992-1994, M. Sci. and B. Sci.: National Autonomous University of Mexico, Sabbatical leave at Harvard and California Universities. he honored with Member of the National Research System since 1994.

Research Interest

Dr. José Federico Del Río Portilla focused on Determination of the structure of scorpion toxins by RMN. Application of accurate measuring to coupling constants in nuclear magnetic resonance. Development of new techniques in nuclear magnetic resonance. Use of novel pulse sequences for the structural elucidation of proteins.

Publications

  • F. del Río Portilla, A. Gaskell, D. Gilbert, J. Ladias and G. Wagner "Solution Structure Determination of h-RPABC14.4 by NMR" Nature Structural Biology, 6 (1999) 1039-1042.

  • Saucedo AL, Flores-Solis D, de la Vega RC, Ramírez-Cordero B, Hernández-López R, Cano-Sánchez P, Navarro RN, García-Valdés J, Coronas-Valderrama F, de Roodt A, Brieba LG. New tricks of an old pattern structural versatility of scorpion toxins with common cysteine spacing. Journal of Biological Chemistry. 2012 Apr 6;287(15):12321-30.

  • Saucedo AL, del Rio-Portilla F, Picco C, Estrada G, Prestipino G, Possani LD, Delepierre M, Corzo G. Solution structure of native and recombinant expressed toxin CssII from the venom of the scorpion Centruroides suffusus suffusus, and their effects on Nav1. 5 sodium channels. Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics. 2012 Mar 31;1824(3):478-87.

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