Molecular Biology
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Molecular Biology Experts

Rossana Arroyo Verátegui

Researcher
Department of Genetics and Molecular Biology.
National Polytechnique Institute
Mexico

Biography

Molecular pathogenesis of trichomonosis (cytoadherence, cytotoxicity and haemolysis). Cysteine ​​proteinases (CPs), CP endogenous inhibitors, and adhesins as virulence factors of Trichomonas vaginalis. Autophagy of hydrogenosomes (hydrogenophagy) as a mechanism of protein relocation to the parasite surface. Gene expression regulation by iron and glucose of virulence factors (cysteine ​​and aspartic proteinases, CP inhibitors, and adhesins) of T. vaginalis. Mechanism of posttranscriptional gene regulation by iron mediated by atypical RNA-binding proteins (cytoskeleton associated and stress response proteins). Recombinant virulence factors as potential targets for diagnosis, treatment and vaccine of T. vaginalis infection.

Research Interest

Dr. Rossana Arroyo Verátegui is affiliated to Department of Genetics and Molecular Biology. , Cinvestav. Dr. Rossana Arroyo Verátegui is currently providing services as Researcher. Dr. Rossana Arroyo Verátegui has authored and co-authored multiple peer-reviewed scientific papers and presented works at many national and International conferences. Dr. Rossana Arroyo Verátegui contributions have acclaimed recognition from honourable subject experts around the world. Dr. Rossana Arroyo Verátegui is actively associated with different societies and academies. Dr. Rossana Arroyo Verátegui academic career is decorated with several reputed awards and funding. Dr. Rossana Arroyo Verátegui research interests include Molecular pathogenesis of trichomonosis (cytoadherence, cytotoxicity and haemolysis). Cysteine ​​proteinases (CPs), CP endogenous inhibitors, and adhesins as virulence factors of Trichomonas vaginalis. Autophagy of hydrogenosomes (hydrogenophagy) as a mechanism of protein relocation to the parasite surface. Gene expression regulation by iron and glucose of virulence factors (cysteine ​​and aspartic proteinases, CP inhibitors, and adhesins) of T. vaginalis. Mechanism of posttranscriptional gene regulation by iron mediated by atypical RNA-binding proteins (cytoskeleton associated and stress response proteins). Recombinant virulence factors as potential targets for diagnosis, treatment and vaccine of T. vaginalis infection..

Publications

  • Mendoza-López MR, Becerril-García C, Fattel-Facenda LV, Avila-González L, Ruiz-Tachiquín ME, Ortega-López J and Arroyo R. 2000. CP30: A cysteine ​​protein involved in Trichomonas vaginalis cytoadheren ce. Infect. Immun. 68 (9): 4907-4912.

  • Alvarez-Sánchez ME, Avila-González L, Becerril-García C, Fattel-Facenda LV, Ortega-Lopez J and Arroyo R. 2000. A novel cysteine ​​proteinase (CP65) of Trichomonas vaginalis involved in cytotoxicity. Microb. Path. 28: 193-202.

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