Bram Bout

Biography

Dr. Abraham (Bram) Bout is Chief Executive Officer and Managing Director of Bioceros, a division of the Polpharma Group. Recently, Bram was VP, Head of Epirus Biopharmaceuticals (Netherlands). He was also Chief Technology Officer at Profibrix BV (Leiden, The Netherlands) from 2007 – 2014. Prior to joining Bioceros (in 2007), he was employed by Crucell (from 1993 till March 2007), where he held several management positions with increasing responsibility. His last position at Crucell was Vice President, Protein Production. Bram is co-inventor of the human PER.C6 production platform which is used for the development and manufacturing of vaccines, monoclonal antibodies, therapeutic proteins and gene therapy products. He studies Chemistry at the University of Amsterdam and his PhD thesis was on peroxisomal storage disorders. He published over 50 scientific articles and is co-inventor on 90 patents about the PER.C6 cell line technology and in the field of recombinant protein production and gene therapy.  

Research Interest

 Manufacturing of vaccines, monoclonal antibodies, therapeutic proteins and gene therapy products