Dr. Bas Zaat
administrative proceedings
Material science
Biosparq B.V.
Netherlands
Biography
S.A.J. Zaat is one of the Amsterdam Academic Medical Center Principal Investigators. Focus of his research: Biomaterial-associated infections and novel antimicrobial strategies. Biomaterial-associated infections, i.e. infections of biomedical devices, or “biomaterials” (catheters, prosthetic heart valves, implants), are a major and increasing problem in modern medicine, especially in view of the increase in antibiotic resistance. Bacterial, biomaterial, and host-responses involved in the pathogenesis are subject of studies, in order to find novel approaches for treatment and prevention. In the NANTICO (Non-adherent ANTImicrobial Coatings) consortium project different antimicrobial coating strategies have been developed to prevent infection. In the IBIZA (Imaging of Biomaterial-associated Infection using a novel model for testing new biomaterials is being developed, and in the BALI (Biofilm Alliance) EU FP7 project we develop novel Synthetic Antimicrobial Antibiofilm Peptides for controlled release coatings to prevent infection of titanium implants. He and Dr. Andrej Trampuz from the Berlin Charité are the driving forces behind a research project where the Biosparq platform is used to treat patients with prosthetic joint infections (PJIs) more effectively.
Research Interest
Biomatwerial, biomedical devices
