Ludovic Vallier

Biography

  Ludovic holds key senior faculty positions at the SANGER institute as well as the University of Cambridge and coordinates and manages large-scale stem cell production activities and disease research grants for multiple bodies including ERC, MRC, Wellcome Trust and NIHR. The Vallier laboratory studies mechanisms controlling the differentiation of pluripotent cells into pancreas and liver cell types. They have advanced the state of the art regarding the use of iPSC as an in vitro model of development. This has included the development of a platform technology enabling the controlled differentiation of human stem cells into specific endodermal cell types including pancreas and liver progenitors. He has created the Cambridge NIHR BRC iPSC core facility and he is now coordinating this large scale HIPSCI project. This aims to derive iPSC lines from 1500 patients within the Sanger Institute and also with institutions worldwide such as the NIH. Ludovic has published several high impact factor articles on iPSCs and are used for modelling liver diseases and cell based therapy. He has also developed a strong interest in pancreatic development by establishing robust protocols of differentiation to generate homogenous population of beta-like cells. Ludovic is a Professor of Regenerative Medicine and Stem Cells.

Research Interest