Stephen Fitzpatrick

Biography

Dr. Stephen (Steve) Fitzpatrick is a Biochemical Engineer and Principal Biotechnology Consultant with DPS. He has over 35 years of experience in the biological, pharmaceutical and chemical process industries and has been published in many leading journals. Steve is the inventor and holds the patents for the Biofine process for conversion of cellulosic biomass into levulinic acid. Steve’s specialist expertise covers a range of technologies, summarized as follows: - Recombinant DNA processes using bacterial, mammalian, viral, transgenic and tissue therapeutic protein sources - Development of large scale bioreactor technology and production scale chromatographic methods for purification of proteins and live virus - Biocontainment - Bacterial fermentation based process optimization via computer modelling - Development and design of processes for chaotrope extraction and protein refolding - Development and design of processes involving various mammalian cell types; human fibroblasts, human fetal kidney cells, dendritic cell lines, hybridomas, CHO cells, and mouse 3T3 cells - Scale up and design of processes for human tissue growth, human RBC decontamination, and cell/tissue processing for autologous, allogeneic, and xenogeneic transplantation - Algae and fungal culture - Plasma Fractionation - Tissue extraction  

Research Interest

 Recombinant DNA processes using bacterial, mammalian, viral, transgenic and tissue therapeutic protein sources - Development of large scale bioreactor technology and production scale chromatographic methods for purification of proteins and live virus - Biocontainment - Bacterial fermentation based process optimization via computer modelling - Development and design of processes for chaotrope extraction and protein refolding - Development and design of processes involving various mammalian cell types; human fibroblasts, human fetal kidney cells, dendritic cell lines, hybridomas, CHO cells, and mouse 3T3 cells - Scale up and design of processes for human tissue growth, human RBC decontamination, and cell/tissue processing for autologous, allogeneic, and xenogeneic transplantation - Algae and fungal culture - Plasma Fractionation - Tissue extracti