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Biochemistry Experts

Huib Ovaa

Professor
Chemical biology of post-translational protein modification
Leiden University
Netherlands

Biography

Huib Ovaa is currently working as the professor of Chemical biology of post-translational protein modification in the department of Chemical Biology, Leiden University, Netherlands.

Research Interest

Chemical biology of post-translational protein modification

Publications

  • Wiemhoefer A., Stargardt A., Linden W.A. van der, Renner M.C., Kesteren R.E. van, Stap J., Raspe M.A., Tomkinson B., Kessels H.W., Ovaa H., Overkleeft H.S., Florea B. & Reits E.A. (2015), Tripeptidyl Peptidase II Mediates Levels of Nuclear Phosphorylated ERK1 and ERK2, Molecular and Cellular Proteomics 14(8): 2177-2193.

  • Banno A., Garcia D.A., Baarsel E.D. van, Metz P.J., Fisch K., Widjaja C.E., Kim S.H., Lopez J., Chang A.N., Geurink P.P., Florea B.I., Overkleeft H.S., Ovaa H., Bui J.D., Yang J. & Chang J.T. (2016), Downregulation of 26S proteasome catalytic activity promotes epithelial-mesenchymal transition, Oncotarget 7(16): 21527-21541.

  • Widjaja C.E., Metz P.J., Bruin G. de, Leestemaker Y., Savas J.N., Phan A.T., Goldrath A.W., Yates J.R., Florea B.I., Overkleeft H.S., Ovaa H. & Chang J.T. (2016), Proteasome degradative activity regulates CD8(+) T lymphocyte metabolism and fate specification, Journal of Immunology 196(1): 133.12.

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