Huy Le

Biography

Huy Le is doing Postdoc in Department of Cancer at Netherlands Cancer Institute.

Research Interest

My PhD is on mechanical regulation of stem cell fate decisions. I identified a force-driven transcriptional rheostat that controls chromatin architecture to finetune gene expression, to control lineage progression during epidermal morphogenesis. I am keen on continuing with this line of research to further understand the mechanisms that rely external cellular signal on nucleus and chromatin level. In brief, I want to know how the nuclear envelope and its components control chromatin architecture as well as transcription in order to define cell response and identity.