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R.a.h. (roger) Adan

Professor
Translational Neuroscience
University Medical Center Utrecht
Netherlands

Biography

Roger Adan was trained as a molecular neurobiologist and received his PhD in 1992 on the regulation of vasopressin and oxytocin gene expression. Since 2002 he is full professor in molecular pharmacology. Via his work on melanocortin receptors he became an expert in molecular and neural pathways underlying feeding behavior, obesity and eating disorders. His lab has a strong multidisciplinary character. A variety of strategies (pharmacogenetics, viral vector technology, in vivo electrophysiology, optogenetics and automated behavioral and physiological analysis) is used to unravel mechanism underlying behavior. The main focus is on feeding, since this is a natural behavior ideally suited to dissect neural circuits that underlie decision making, anxiety, anhedonia, impulsivity and reward seeking. Roger Adan was trained as a molecular neurobiologist and received his PhD in 1992 on the regulation of vasopressin and oxytocin gene expression. Since 2002 he is full professor in molecular pharmacology. Via his work on melanocortin receptors he became an expert in molecular and neural pathways underlying feeding behavior, obesity and eating disorders. His lab has a strong multidisciplinary character. A variety of strategies (pharmacogenetics, viral vector technology, in vivo electrophysiology, optogenetics and automated behavioral and physiological analysis) is used to unravel mechanism underlying behavior. The main focus is on feeding, since this is a natural behavior ideally suited to dissect neural circuits that underlie decision making, anxiety, anhedonia, impulsivity and reward seeking.

Research Interest

"Brain Circulatory Health"

Publications

  • Li D, Chang X, Connolly JJ, Tian L, Liu Y, Bhoj EJ, Robinson N, Abrams D, Li YR, Bradfield JP, Kim CE. A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling. Scientific reports. 2017 Jun 19;7(1):3847.

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