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Ir. J. (jos) Malda


Department of Equine Sciences - Equine Muscoskeletal Biology
Utrecht University
Netherlands

Biography

Our research group focuses on biofabrication and biomaterials design, in particular for the regeneration of (osteo) chondral defects. We are developing novel biofabriaction strategies, as well and “bioinks” for 3D printing. These hydrogel-based “inks” are both designed to drive specific differentiation of the embedded and/or endogenous cells, as well as to allow fabrication with high shape fidelity in order to generate constructs that are a blueprint of the real tissue. In addition, we are adopting bioreactor technology to mature the generated tissue constructs. Finally, approaches towards the translation of the constructs in veterinary (equine) and human clinics are pursued, including its use as an in vitro platform for testing.

Research Interest

Biomaterial development

Publications

  • Mouser, Vivian Hilda Maria, Abbadessa, Anna, Levato, Riccardo, Hennink, Wim, Vermonden, Tina, Gawlitta, Debby & Malda, Jos (23.02.2017). Development of a thermosensitive HAMA-containing bio-ink for the fabrication of composite cartilage repair constructs. Biofabrication © 2017 IOP Publishing Ltd..

  • Schneeberger, Kerstin, Spee, Bart, Costa, Pedro, Sachs, Norman, Clevers, Hans & Malda, Jos (17.02.2017). Converging biofabrication and organoid technologies - the next frontier in hepatic and intestinal tissue engineering?. Biofabrication Copyright 2017 IOP Publishing Ltd..

  • Zadpoor, Amir A & Malda, Jos (2017). Additive Manufacturing of Biomaterials, Tissues, and Organs. Annals of Biomedical Engineering, 45 (1), (pp. 1-11).

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