L.c. (lukas) Kapitein
Biology - Biodynamics and Biocomplexity - Cell Biology
Utrecht University
Netherlands
Biography
Our goal is to obtain a physical understanding of the mechanisms by which cells establish and maintain their precise shape and intracellular organization. We focus on the cytoskeleton, a mechanical network of biopolymers and associated proteins that gives the cell its shape and strength. Motor proteins can move over these biopolymers to deliver cargo to specific subcellular compartments or to reorganize the fibers themselves.
Research Interest
cell biology
Publications
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Yau, Kah Wai, Schätzle, Philipp, Tortosa, Elena, Pagès, Stéphane, Holtmaat, Anthony, Kapitein, Lukas C & Hoogenraad, Casper (27.01.2016). Dendrites In Vitro and In Vivo Contain Microtubules of Opposite Polarity and Axon Formation Correlates with Uniform Plus-End-Out Microtubule Orientation. Journal of Neuroscience, 36 (4), (pp. 1071-85) (15 p.). Copyright © 2016 the authors 0270-6474/16/361072-15$15.00/0..
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Noordstra, Ivar, Liu, Qingyang, Nijenhuis, Wilco, Hua, Shasha, Jiang, Kai, Baars, Matthijs, Remmelzwaal, Sanne, Martin, Maud, Kapitein, Lukas & Akhmanova, Anna (15.11.2016). Control of apico-basal epithelial polarity by the microtubule minus-end-binding protein CAMSAP3 and spectraplakin ACF7. Journal of Cell Science, 129 (22), (pp. 4278-4288) (11 p.). © 2016. Published by The Company of Biologists Ltd..
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van Riel, Wilhelmina E, Rai, Ankit, Bianchi, Sarah, Katrukha, Eugene A, Liu, Qingyang, Heck, Albert Jr, Hoogenraad, Casper C, Steinmetz, Michel O, Kapitein, Lukas C & Akhmanova, Anna (2017). Kinesin-4 KIF21B is a potent microtubule pausing factor. eLife, 6 (30 p.).
