M.m.s.m. (marc) Wösten
Departement Infectieziekten en Immunologie - Infectiebiologi
Utrecht University
Netherlands
Biography
Marc Wösten is an expert in bacterial genetics. His main interest is to unravel the basic mechanisms by which bacteria can adapt to their environment. During his PhD under supervision of Prof. B.A.M. van der Zeist he studied the mechanisms of gene transcription in the pathogen Campylobacter jejuni, He spent two years of research as a post-doctoral fellow in the laboratory of Dr. Eduardo Groisman (Howard Hughes Medical Institute, St. Louis, USA) to investigate two-component signal transduction systems in Salmonella typhimurium. In order to be better able to position this type of work in the natural setting of an infection, he became a post-doc at the National Institute of Public Health and Environment (RIVM) in Bilthoven to work on the interaction of epithelial cells with the respiratory pathogen Haemophilus influenzae. In the year 2001, he was granted a KNAW fellowship that allowed him to combine his expertise on Campylobacter genetics, two-component systems and bacteria-host interactions. In 2005 he obtained NWO-VIDI grant that allowed him to continue to work on the two-component systems of C. jejuni that are involved in the secretion of virulence associated proteins through the flagellar nano-secretion machinery. Since 2005 he is an Assistant Professor at the division Infection Biology.
Research Interest
Infection and Immunity
Publications
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Radomska, Katarzyna A, Wösten, Marc M S M, Ordoñez, Soledad R, Wagenaar, Jaap A & van Putten, Jos P M (2017). Importance of Campylobacter jejuni FliS and FliW in Flagella Biogenesis and Flagellin Secretion. Frontiers in Microbiology, 8, (pp. 1060).
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van der Stel, Anne-Xander, Boogerd, Fred C, Huynh, Steven, Parker, Craig T, van Dijk, Linda, van Putten, Jos P M & Wösten, Marc M S M (06-06-2017). Generation of the membrane potential and its impact on the motility, ATP production and growth in Campylobacter jejuni. Molecular Microbiology © 2017 John Wiley & Sons Ltd..
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Wösten, Marc M S M, van de Lest, Chris H A, van Dijk, Linda & van Putten, Jos P M (07-02-2017). Function and Regulation of the C4-Dicarboxylate Transporters in Campylobacter jejuni. Frontiers in Microbiology, 8, (pp. 174).
