R. (rolf) Boelens
Chemistry - Biomolecular Sciences - NMR Spectroscopy
Utrecht University
Netherlands
Biography
We study structure and dynamics of protein and protein-DNA complexes involved in gene regulation, transcription and DNA repair. For this research we use high-resolution NMR and develop new methodology as well.
Research Interest
NMR spectrotrophy
Publications
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Zhang R, Loers G, Schachner M, Boelens R, Wienk H, Siebert S, Eckert T, Kraan S, Rojas-Macias MA, Lütteke T, Galuska SP, Scheidig A, Petridis AK, Liang S, Billeter M, Schauer R, Steinmeyer J, Schröder JM, Siebert HC (2016) Molecular Basis of the Receptor Interactions of Polysialic Acid (polySia), polySia Mimetics, and Sulfated Polysaccharides, ChemMedChem 11, 990-1002
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A Vavrinska, J Zelinka, J Sebera, V Sychrovsky, R Fiala, R Boelens, V Sklenar, L Trantirek (2016) Impact of nucleic acid self-alignment in a strong magnetic field on the interpretation of indirect spin-spin interactions, J Biomol NMR 64, 53-62, and erratum in J Biomol NMR 65 (2016), 49
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D Das, M Faridounnia, L Kovacic, R Kaptein, R Boelens and GE Folkers (2017) Single-stranded DNA Binding by the Helix-Hairpin-Helix Domain of XPF Protein Contributes to the Substrate Specificity of the ERCC1-XPF Protein Complex, J Biol Chem. 292, 2842-2853, DOI: 10.1074/jbc.M116.747857
